WRD is interested in establishing alliances to develop and access:
- Mechanisms, biomarkers, and screening approaches related to target organ toxicity
- Cardiovascular safety
- Liver injury
- Hypersensitivity
- Nephrotoxicity — esp., glomerular
- Skeletal and cardiac muscle toxicity
- Ocular safety
- Screening for abuse potential
- Biotherapeutics
- Immunogenicity and other safety relevant assays
- Deeper knowledge of targets and pathways
- Knock-in, knock-out technologies
- Humanized animal models
- Novel technologies and increased throughput for target localization studies
- Safety Biomarker Technologies
- Platforms; multiplex; analytical approaches; validated reagents
Not actively seeking partnering opportunities in:
- Genetox Screening
- hERG related assays
- In vitro screening models without significant validation
- In silico approaches without experimental validation
