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Immunoscience

immunology-and-autoimmunity

Pfizer is a global leader in developing medicines for patients suffering from chronic immune diseases. Pfizer's commitment to the discovery and development of novel therapeutics to help patients living with chronic autoimmune diseases is evidenced by products such as Xeljanz® (tofacitinib citrate), Celebrex® (celecoxib capsules), Rapamune® (sirolimus), and Enbrel® (etanercept) for patients suffering from conditions such as osteoarthritis, solid organ transplant rejection, rheumatoid arthritis, and psoriasis. Pfizer is interested in entering into strategic relationship with innovative collaborators to develop increasingly novel and differentiated therapies for autoimmune diseases.

WRD is interested in establishing alliances to develop therapeutics, expand disease biology understanding, and identify biomarkers that impact:

  • Rheumatoid Arthritis
  • Systemic Lupus Erythematosus
  • Inflammatory Bowel Disease
  • Psoriasis
  • Multiple Sclerosis and smaller indications with high unmet need that are mechanistically related to those above

Specific areas of interest include:

  • Cytokines and their signaling pathways
  • Adaptive Immunity, Lymphocyte biology including Th17 lymphocytes
  • Regulatory cells and Tolerance induction
  • Host-microbial interactions and microbiome
  • Technology platforms and products to help understand patient segmentation in the disease areas of interest and develop precision medicine strategies for innovative portfolio products

Not actively seeking partnering opportunities in:

  • Adequately controlled RA
  • TNFα, IL-1β targeting biologics
  • B cell depleting biologics
  • Corticosteroids

 

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Understand what R&D is looking for in an early stage opportunity.

 

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