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Product Pipeline

Product Pipeline

Our Medicines in Development

Pfizer is prioritizing its research and development efforts in areas with the greatest scientific and commercial promise: immunology and inflammation, oncology, cardiovascular and metabolic diseases, neuroscience and pain, and vaccines. Through major research efforts across multiple modalities — including small molecules, biologics and vaccines — Pfizer is developing the medical solutions that will matter most to the people we serve. Specialized efforts in biosimilars as well as rare diseases also illustrate our dedication to developing and delivering innovative medicines and vaccines that will benefit patients around the world.

Key Programs in Registration / Phase 3

  • Ertugliflozin: Type 2 Diabetes (in collaboration w/ Merck)
  • Infliximab: Rheumatoid Arthritis
  • Palbociclib: Advanced Breast Cancer (1st Line & Recurrent), High Risk Early Breast Cancer
  • PCSK9 Inhibitor (bococizumab/RN316): Hyperlipidemia
  • Prophylactic Vaccine for Meningococcal Serogroup B (ex-U.S.)
  • Rituximab: Follicular Lymphoma
  • Trastuzumab: Breast Cancer
  • Vyndaqel (tafamidis meglumine): Cardiomyopathy
  • Xeljanz® (tofacitinib): Ulcerative Colitis, Psoriasis (oral) Psoriatic Arthritis

Key Programs in Phase 2

  • Anti-IL-6 Antibody: Crohn’s Disease, Lupus
  • Anti MadCAM: Crohn’s Disease, Ulcerative Colitis
  • CCR2/5 Antagonist: Diabetic Nephropathy, Diabetic Macular Edema
  • PDE5 Inhibitor: Diabetic Nephropathy
  • PDE10 Inhibitor: Huntington's Disease
  • PI3K/mTOR Inhibitor: Colorectal Cancer
  • Prophylactic Vaccine for Clostridium difficile Colitis
  • Prophylactic Vaccine for Staphylococcus aureus
  • Rivipansel: Sickle Cell Disease
  • SMO Inhibitor: Acute Myeloid Leukemia
  • Xeljanz® (tofacitinib): Crohn's Disease, Ankylosing Spondylitis, Psoriasis (topical), Atopic Dermatitis
  • 5HT6 Antagonist (SAM-760): Alzheimer's Disease