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System for Dosing and Dispensing Multiparticulate Formulations of Pediatric Drugs Request for Proposals (RFP)


The Institute for Pediatric Innovation (IPI) and Pfizer are collaborating on an open innovation challenge to solicit and support innovative ideas for a system consisting of a package and dispensing device that will be used to deliver oral solid multiparticulate (MP) medicines to children. Parties entering the competition including the winning entity will retain ownership of related intellectual property, as Pfizer and IPI intend that the party submitting the winning design commercialize the design independently either directly or through a partner. The organization who submits the winning design will be awarded a seed grant to fund ‘proof of concept’ steps toward development of the device, and will have the opportunity for ongoing liaison with IPI to access its networks to explore follow-on funding opportunities.

Pfizer has developed a formulation technology that addresses taste, storage, and other factors essential for safe, accurate, and adherent administration of medicines to children in low-resource global health settings

What do we want to achieve?

We welcome proposals for the design of a device that can measure and administer a drug multiparticulate formulation in a child friendly but child-misuse resistant format and in doses relevant for therapy in low resource settings

Which expertise do we seek?

We seek ideas from individuals or groups who understand the challenges of the low resource setting and are eager to address these challenges with their device design. We are looking for people with experience in, but not limited to, device design, drug dispensing, and human factors design. We believe that “less is more” and that we can minimize device complexity while maximizing device utility.

What are the evaluation criteria?

A review committee, led by IPI and composed of engineers, end users, and experts, will make decisions on which proposals will receive funding. Grant funding will be provided by Pfizer. Up to $50,000 is available for the award(s).

The proposals will be evaluated on:

  1. Dose accuracy
  2. Cost
  3. End user ease of use
  4. Cultural appropriateness

Click here to view the Request for Proposal posting.

Click here to view the Budget Template*.

*The budget template is ONLY required at the Full Proposal stage.

Posting Date March 28, 2016
Q&A Session April 12, 2016
Letter of Intent (LOI) due May 16, 2016
LOI decision notifications On or about June 10, 2016
Full Proposal due July 22, 2016
Winner announced On or about August 19, 2016

The Institute for Pediatric Innovation (IPI) is a nonprofit organization focused on developing new medical devices and medicines specifically for children. The IPI team recognizes that pediatric healthcare is a niche – often neglected – market and forms relationships with various organizations to ensure that creative, feasible, and sustainable medical products become commercially available.

At Pfizer, we apply science and our global resources to bring therapies to people that extend and significantly improve their lives. We strive to set the standard for quality, safety and value in the discovery, development and manufacture of health care products. Our global portfolio includes medicines and vaccines as well as many of the world's best-known consumer health care products. Every day, Pfizer colleagues work across developed and emerging markets to advance wellness, prevention, treatments and cures that challenge the most feared diseases of our time. Consistent with our responsibility as one of the world's premier innovative biopharmaceutical companies, we collaborate with health care providers, governments and local communities to support and expand access to reliable, affordable health care around the world. For more than 150 years, Pfizer has worked to make a difference for all who rely on us

If you have any questions regarding this RFP, please direct them in writing to the Grant Officer Amanda Stein ([email protected]) and to the IPI Coordinator Winnie Wong ([email protected]) with the subject line “Multiparticulate Device RFP”. The questions will then be triaged and referred to the appropriate party for feedback and response.

In addition, Justin Starbird ([email protected]) from the Aebli Group has been engaged to help spread the word of this RFP. Justin will also be able to triage questions.

Please click here to listen to the informational conference call that was held on Tuesday, April 12, 2016. This call provided an overview of the challenge as well as answers to questions asked by the attendees.

The Request for Proposals

Please click here to view the full Request for Proposals (RFP)