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"The industry gold standard for a pharmaceutical process in which solvent usage and recycling scenarios are considered would be the Viagra (sildenafil) process... The details of this manufacturing process were disclosed, and more importantly, significant development efforts were undertaken to set this benchmark for the pharmaceutical industry." – A Green Chemistry Comparative Analysis, authored by Michael A. Kuzemko, Susan D. Van Arnum, and Henry J. Niemczyk (Organic Process Research and Development, 2007, 11, 470-476)
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