Sorry, you need to enable JavaScript to visit this website.
Skip to main content
Home

Header Top Menu

  • Careers
  • Investors
  • News
    • Press Release Archive
    • Press Statements
    • Podcasts
      • The Antigen Podcast
      • Get Science Podcast
      • Diverse Perspectives Podcast
      • menopause: unmuted
      • Hemcast
    • Contact Media Relations
    • Press Kits & Downloads
      • Company Press Kit
      • Pfizer Oncology Press Kit
      • PSA Narrative
      • RA NarRAtive
      • Rare Disease Gene Therapy Press Kit
      • ATTR-Amyloidosis Press Kit
      • UC Narrative
      • Eczema Inside Out Press Kit
  • Partners
    • Discovery to Pre-candidate
      • Focus Areas
        • Therapeutic Areas
          • Internal Medicine
          • Inflammation and Immunology
          • Oncology
          • Rare Disease
          • Vaccines
        • Therapeutic Modalities and Technology Platforms
          • Drug Safety
          • Gene Therapy
          • Target Sciences
          • Precision Medicine
          • Medicinal Sciences
            • Biologics Product & Process Development
            • Biotherapeutics Discovery
            • Medicine Design
            • Small Molecule Product & Process Development
        • Emerging Science
          • DNA Damage Response
          • Microsatellite Repeat Expansions
          • Senescence
      • Partnering Models
    • Candidate Through Commercialization
      • Focus Areas
        • Internal Medicine
        • Inflammation and Immunology
        • Oncology
        • Rare Disease
        • Vaccines
        • Hospital
    • Pfizer CentreOne
    • Pfizer Ventures
      • Our portfolio

Healthcare Professionals

  • Healthcare Professionals

Connect with Us

  • Connect with Us
    • Email
    • FAQ
    • Privacy Policy (NEW)
    • YouTube
    • Twitter
    • Facebook
    • LinkedIn
    • Instagram
  • Your Health

    • Healthy Living
      • Brain & Nervous System
      • Cardiovascular Health
      • Cold & Flu
      • Digestive Health
      • Healthier Aging
      • Living Tobacco Free
      • Men’s Health
      • Mental Health
      • Nutrition & Fitness
      • Pediatric Health
      • Respiratory Health
      • Skin Health
      • Vaccines & Prevention
      • Women’s Health

    • Disease & Condition
      • Cancer
      • Cardiovascular Diseases & Conditions
      • Diabetes & Metabolic Disorders
      • Immune System Diseases & Conditions
      • Infections & Infectious Diseases
      • Neurological Diseases & Conditions
      • Menopause
      • Rare Disease
      • Vaccine-Related Conditions
      • Skin Diseases & Conditions
      • Atopic Dermatitis
      • Cardiovascular Disease
      • Severe Hypertriglyceridemia

    • Coronavirus disease (COVID-19) Resources

    • Managing your health
      • Caregiving
      • Evaluating Health Information
      • Tracking Your Health
      • Your Medicines
      • Health Literacy

    • Wellness
    Hot Topics

    Maintaining Emotional Well-Being During COVID-19

    Emotional Well-Being Tips for People Living with Chronic Inflammatory Conditions During COVID-19
  • Our Science

    • Driven to Discover the cure

    • Focus Areas
      • Internal Medicine
      • Inflammation & Immunology
      • Oncology
      • Rare Disease
      • Vaccines
      • Anti Infectives

    • Product Pipeline

    • Clinical Trials
      • Guide to Clinical Trials
      • Find a Trial
      • Expanded Access & Compassionate Use
      • Clinical Trials in Children
      • Partnering with Pfizer
      • Trial Data & Results
      • Research Integrity & Transparency
      • Diversity in Clinical Trials

    • R&D Platforms
      • Biosimilars
      • Gene Therapy
      • Medicinal Sciences
      • Precision Medicine
      • Maternal Immunization

    • Collaboration
      • Partner with Pfizer

    • Research sites

    • Coronavirus disease (COVID-19) Resources
      • All COVID-19 Updates
      • Vaccine Efforts
      • Antiviral Efforts
      • Partnerships & Anti-Infective Efforts
      • Supporting the Fight Against COVID-19
    HOT TOPICS

    MRNA VS. CONVENTIONAL VACCINES

    What Makes an RNA Vaccine Different From a Conventional Vaccine?
  • Our People

    • Meet The Experts
      • Scientists
      • Internal Medicine – Metabolic Disease
      • Inflammation & Immunology
      • Oncology
      • Rare Disease
      • Vaccines
      • Medical Professionals

    • The Journey

    • Leadership
      • Executives
      • Board Members
      • Company Fact Sheet

    • Diverse Perspectives
      • Diversity & Inclusion
      • Supplier Diversity
    HOT TOPICS

    Meet our new Chief Patient Officer, Dr. Dara Richardson-Heron

    dr_richardson_300x170.jpg

    Working Together to Empower Women

    VizagWomen_300x170.jpg

    • Hot Topics
  • Our Purpose

    • Commitment to Global Health
      • Expanding Access
      • Strengthening Health Systems
      • Providing Disaster & Humanitarian Relief
      • Unleashing the Power of Our Colleagues
      • Highlighting Individual Voices

    • Protecting People and the Environment
      • Pfizer's Green Journey
      • Product Stewardship
      • EHS Governance
      • EHS Supply Chain
      • Key Performance Indicators
      • Health & Safety
      • Human Rights

    • Positions on Health Policies
      • Ready for Cures
      • How does Pfizer price medicines?
      • Value of Medicines
      • Policy Positions
      • Creating Cures Through Facility Investments

    • Transparency
      • Working with Health Care Professionals
      • Transparency in Grants
      • Code of Conduct
      • Corporate Compliance
      • Sales and Marketing Compliance

    • Independent Grants
      • Competitive Grants Program
      • Independent Medical Education
      • Investigator Sponsored Research
      • Quality Improvement
      • COVID-19 Vaccine Grants

    • Contributions & Partnerships
      • Healthcare Charitable Contributions
      • Lobbying & Political Contributions
    HOT TOPICS

    Pfizer Women’s Resource Group

    Media Name: IWD_Pull_up_Banner_300x170.jpg

    • Hot Topics
  • Our Products

    • Product listing

    • How drugs are made
      • Branded vs. Generic
      • Biologics & Biosimilars
      • Commitment to Quality

    • Distributors
      • Pfizer Distributors
      • Greenstone Distributors

    • Medicine Safety
      • Reporting Adverse Events
      • Making Good Treatment Choices
      • Partnering With Patients
      • Health Literacy
      • Medicine Safety Tips for Patients
      • Counterfeiting
      • Unused Medicines

    • Safety Data Sheets

    • Medical Information Contacts

    • Pfizer Global Supply
    HOT TOPICS

    Universal vs. Single Payer Healthcare

    Media Name: universal_healthcare300x170.jpg
  • Careers

    • Working Here
      • Mission & Purpose
      • Culture
      • Diversity & Inclusion
      • Career Growth & Colleague Development
      • Compensation & Benefits
      • Ensuring Corporate Responsibility
    • Search Jobs
    • Student & Early Career
      • Postdoctoral Program
      • US Summer Student Worker Program
      • Opportunities for Veterans
    • Pfizer365.com
    • Our Hiring & Recruiting Process
      • Frequently Asked Questions
      • Tips for Interviewing at Pfizer
    • Connect With Us
  • Investors

    • Investors Overview
      • Why Invest / Our Story
      • Prospective Investors
      • Fact Sheet
    • Events & Presentations
    • Financials
      • Quarterly Reports
      • Annual Reports
      • SEC Filings
      • Interactive Data Filings
    • Investor News
    • Stock Information
      • Historical Price Lookup
      • Investment Calculator
      • Historical Stock Chart & Data
      • Dividend & Split History
      • Stock FAQs
    • Governance
      • Board Committees and Charters
      • The Pfizer Board Policies
      • Corporate Governance FAQs
      • Contact Our Directors
    • Shareholder Services
      • Stock FAQs
      • Advisory Information
      • Cost Basis Calculator
  • News

    • Contact Media Relations
    • Podcasts
    • Press Kits & Downloads
    • Press Release Archive
    • Press Statements
  • Partners
  • Footer links

    • Footer Aside Section1
      • CAREER-SEEKERS
      • INVESTORS
      • News & Media
      • Partners
    • Footer Aside Section 2
      • Healthcare Professionals
      • Business To Business
      • Change Region
      • Sitemap
    • Footer Aside Section3
      • Twitter
      • Facebook
      • Linkedin
      • Instagram
      • Youtube
    • Footer Aside Section4
      • Contact Us
      • Terms of Use
      • Privacy Policy
OUR PURPOSE/ The Value of Vaccines in Disease Prevention: A Global Perspective
December 14, 2020

Vaccinations are an essential tool in our fight against infectious disease. According to the World Health Organization (WHO), vaccination has greatly reduced the burden of infectious disease globally.1 Vaccines protect the vaccinated individual by direct immunization and can protect unvaccinated individuals through community protection or herd immunity, vaccination of a significant portion of the population to protect against the spread of contagious disease.2 Vaccination has also been highlighted as one of the main reasons for reducing health disparities both within and across countries in the last century, though racial and ethnic differences in vaccination rates still persist.3,4

2-3_million_infographic.png

According to the World Health Organization (WHO), immunizations save an estimated 2-3 million lives each year from vaccine-preventable infections.5

It is well-documented that some vaccines decrease antibiotic use, thus lowering the likelihood of antibiotic resistance.6 This suggests that vaccines can play a role in decreasing antibiotic resistant infections.2 The Centers for Disease Control and Prevention (CDC) now advocates for the development of and improved access to vaccines as a tool for addressing antimicrobial resistance (AMR).7

SOCIETAL HEALTH IMPACT

Vaccines have dramatically reduced the threat of diseases that were once widespread and oftentimes fatal.8 Today, more people benefit from safe and effective vaccines than ever before — and the list of diseases that vaccines can help to prevent continues to grow. Vaccines help reduce health care costs to both patients and the broader health care system by reducing the incidence of vaccine-preventable illness including associated hospitalizations and death.8 Continued investment in new vaccine technologies is critical for the development of new and more effective ways to address unmet medical needs.

26_million_cases_infographic.png

It is estimated that vaccinations prevented 26 million cases of childhood disease in the U.S. in the past decade, representing approximately 99 percent of diseases that would have occurred.9


prevented_an_estimated_infographic.png

Routine vaccination with Hepatitis B vaccine in China has prevented an estimated 120 million infections, including 28 million chronic infections, between 1992 and 2014. By preventing these infections, many individuals averted hepatitis B-associated liver cirrhosis and/or cancer.10


vaccines_can_prevent_infographic.png

AMR is a significant public health problem, negatively impacting millions of people worldwide and costing billions of dollars. Vaccines can help by (1) preventing an individual from ever developing an infection which requires antibiotic treatment, and (2) reducing the transmission and circulation of certain types of bacteria strains that are antibiotic resistant.11

ECONOMIC IMPACT

Timely use of vaccinations and adherence to the WHO’s recommended vaccination schedules for infants, children, and adults prevent morbidity and mortality, and save millions of dollars in direct medical costs to the health care system and prevent indirect costs associated with the illnesses.12 The further development and appropriate implementation of new, innovative vaccines may continue to cut costs.

for_every_for_adults_infographic.png

in_a_recent_study_infographic.png

In a recent study, it was estimated that routine childhood vaccination in U.S. children born in 2009 would be valued over their collective lifetimes at $8.9 billion for measles vaccination, $2.7 billion for pneumococcal disease, and $595 million for rotavirus.15

the_ability_to_prevent_infographic.png

The ability to prevent 20 million deaths by vaccinating children and adults against ten vaccine-preventable diseases has a total estimated economic and social value of $820 billion in low- and middle-income countries.14

in_2015_infections_infographic.png

In 2015, infections from vaccine-preventable diseases in unvaccinated individuals cost approximately $7.1 billion in the U.S.12 This included 4,450 cases of pertussis, with an average cost of $600 per case.14 Given that the pertussis vaccine costs between $25-44, significant cost savings could have been realized through vaccination.16

a_recent_modeling_infographic.png

A recent modeling study estimated that routine childhood immunization among children born in the U.S. between 1994 and 2013 will prevent an estimated 322 million illnesses, 21 million hospitalizations, and 732,00 deaths over the course of their lifetimes, with a net savings of $295 billion in direct costs and $1.38 trillion in total societal costs.17

Cost of Outbreaks Around the World

Globally, vaccinations help save billions of dollars by reducing the need for additional healthcare related costs. Between 2001 and 2020 in 73 low- and middle-income countries, avoiding costs of treatment for vaccine-preventable diseases saves $4.6 billion; avoiding lost wages of caretakers saves $886 million; avoiding long-term costs of lost productivity due to disability and death may add savings of around $341 billion.18 Evidence also indicates that increases in vaccination rates lead to economically significant and sustained increases in the gross domestic product (GDP) growth rate.19

11.2_billion_in_costs_infographic.png

Seasonal Influenza in the United States

Less than half of the U.S. population is vaccinated for influenza each year, leading to direct health care costs and indirect productivity costs related to absenteeism from paid employment. Based on 2015 population numbers, there were 26.2 million cases of seasonal influenza in the U.S. with a total annual economic burden of $11.2 billion. Of those costs, $3.2 billion were for direct healthcare costs and $8.0 billion for indirect costs. Persons aged 65 and older had the largest share of total direct costs, primarily due to hospitalizations.20

3.9_million_in_costs_infographic.png

Measles Outbreak in the Netherlands

A measles outbreak in 2013-2014 in the Netherlands resulted in 2,700 measles cases (mostly in children) with a total economic burden of approximately €3.9 million. Even with a national plan to manage the outbreak, restricting the spread of measles was difficult and there were reported cases linked to this outbreak in Canada, the United States, and Belgium.21

384,594_in_costs_infographic.png

Measles Outbreak in the Beijing

A 2015 measles outbreak in Beijing lasted 19 days and resulted in 22 reported cases of measles (all in unvaccinated adults). Controlling the outbreak cost $384,594 and required 21,471 personnel hours.22

48,682_in_costs_infographic.png

Pertussis Outbreak in Amsterdam

Health care workers (HCWs) exposed to infectious diseases are positioned to transfer the disease to susceptible patients. Vaccinating HCWs can help prevent costly outbreaks. A recent study found that a pertussis outbreak on the neonatal ward in Amsterdam cost €48,682, but preventively vaccinating HCWs would only have cost €12,208, suggesting that €4 could be saved for every €1 spent on vaccinating HCWs.23

VACCINE INNOVATION

The development and use of newer innovative vaccines helps us fight infectious diseases that had been previously difficult to vaccinate against. Since new strains are constantly emerging, the ability to develop innovative vaccines is important to meet emerging infectious disease challenges. Vaccines have proven to be an extremely effective way to prevent morbidity and mortality associated with infectious disease. CDC epidemiological surveillance demonstrates up to 99 to 100 percent reduction in several life-threatening infectious diseases in the U.S., as shown in the adapted table below.

the_role_of_vaccines_infographic.png

ENDNOTES

1. United States Fund for UNICEF. (n.d.). Immunization for All Children: Think BIG. Retrieved from www.unicefusa.org/work/immunization/?gclid=CJbxlOK0mr0CFbBj7Aod0noAcg. | 2.Andre, F. E., et al. (2008). Vaccination greatly reduces disease, disability, death and inequity worldwide. Bulletin of the World Health Organization. 86(2):81-160. | 3. See: www.hhpronline.org/articles/2018/7/21/the-equity-and-poverty-reduction-benefits-of-vaccines. | 4. See: https://www.cdc.gov/vaccines/imz-managers/coverage/adultvaxview/pubs-resources/NHIS-2016.html | 5. See: www.who.int/features/factfiles/immunization/en. | 6. Zhou, F., et al. (2008). Trends in acute otitis media-related health care utilization by privately insured young children in the United States, 1997-2004. Pediatrics. 121(2):253-60. | 7. See: www.cdc.gov/drugresistance/intl-activities/amr-challenge.html. | 8. U.S. Department of Health and Human Services. (n.d.). 2020 Topics & Objectives; Immunization and Infectious Diseases. Retrieved from www.healthypeople.gov/2020/topics-objectives/topic/immunization-and-infectious-diseases. | 9. Van Panhuis, W.G., et al. (2013). Contagious disease in the United States from 1888 to the present. NEJM. 369(22):2152-8. | 10. See: http://www.wpro.who.int/china/mediacentre/releases/2018/20180803-Immunizations-Save-Lives/en/. | 11. See: www.pfizer.com/files/health/PFE_AMR_VOM_FINAL_AUG2017_UPDATED.pdf. | 12. See: apps.who.int/immunization_monitoring/globalsummary/schedules. | 13. Adult Vaccine Access Coalition. 2016. The value and imperative of quality measures for adult vaccines. Retrieved from www.adultvaccinesnow.org/wp-content/uploads/2016/07/Value-Imperative-Adult-Vaccines-Final.pdf. | 14. The ten vaccine-preventable pathogens are: Haemophilus influenzae type b, Hepatitis B virus, Human papillomavirus, Japanese encephalitis virus, Measles virus, Neisseria meningitidis serogroup A, Rotavirus, Rubella virus, Streptococcus pneumoniae, and Yellow fever. Ozawa, S., et al. (2017). Estimated economic impact of vaccinations in 73 low- and middle-income countries, 2001-2020. Bull World Health Organ 95:629-38. Retrieved from https://www.who.int/bulletin/volumes/95/9/16-178475.pdf. | 15. Zhou, F., et al. (2014). Economic evaluation of the routine childhood immunization program in the United States, 2009. Pediatrics. 133(4):577–85. | 16. See: www.cdc.gov/vaccines/programs/vfc/awardees/vaccine-management/price-list. | 17. Whitney, C. (2014) Benefits from Immunization During the Vaccines for Children Program Era — United States, 1994–2013. Retrieved from www.cdc.gov/mmwr/preview/mmwrhtml/mm6316a4.htm. | 18. Ozawa, S., et al. (2017). Estimated economic impact of vaccinations in 73 low- and middle-income countries, 2001–2020. Bulletin of the World Health Organization. 95(9):629–38. | 19. Masia, N.A., et al. (2018). Vaccination and GDP growth rates: Exploring the links in a conditional convergence framework. World Dev. 103:88-99. | 20. Putri, W.C.W.S., et al. (2018). Economic burden of seasonal influenza in the United States. Vaccine. 36(27):3960-6. | 21. Suijkerbuijk, A.W.M., et al. (2015). Economic Costs of Measles Outbreak in the Netherlands, 2013–2014. Emerg Infect Dis. 21(11):2067–9. | 22. Ma, R., et al. (2017). An expensive adult measles outbreak and response in office buildings during the era of accelerated measles elimination, Beijing, China. Vaccine. 35(8):1117–23. | 23.Tariq, L., et al. (2015). Modelling the return on investment of preventively vaccinating healthcare workers against pertussis. BMC Infectious Diseases. 15(1):75. | 24. Roush, S. W. (2007). Historical Comparisons of Morbidity and Mortality for Vaccine-Preventable Diseases in the United States. JAMA. 298(18): 2155-63. https://doi.org/10.1001/jama.298.18.2155. | 25. See: https://wonder.cdc.gov/nndss/static/2017/annual/2017-table1.html.

Issued by Global Policy

pfizer-rxpathways-logo

Download this Value of Vaccines in Disease Prevention: A Global Perspective in PDF format.

KEY TAKEAWAYS

According to the World Health Organization (WHO), immunizations save an estimated 2-3 million lives every year.5


The ability to prevent 20 million deaths by vaccination against ten vaccine-preventable diseases has a total estimated economic and social value of $820 billion in low- and middle-income countries.14


In the U.S., immunization of infants born in 2009 would save an estimated $13.5 billion in direct costs over their collective lifetimes.11

Related Hot Topics
Media Name: value_of_medicines_logo_bg300x170_2.jpg
The Value of Vaccines in Disease Prevention in Latin America
Value of Medicines Viewpoint: Patient Perspectives
Value of Medicines Viewpoint: Patient Perspectives
Addiction and Overdose is on the Rise among Baby Boomers—How Much Do You Know?
Addiction and Overdose is on the Rise among Baby Boomers—How Much Do You Know?
Media Name: value_of_medicines_logo_bg300x170_2.jpg
Value Of Medicine: A Report on How Medicines Impact Lives
Tags
Value of Medicines
Show
Hide

Footer menu

  • Your Health
    • Healthy Living
    • Disease Conditions
    • Manage Your Health
  • Our Science
    • Therapeutic Areas
    • Product Pipeline
    • Clinical Trials
    • R&D Platforms
    • Collaboration
    • Research SItes
  • Our People
    • Meet the Experts
    • The Journey
    • Leadership
    • Diverse Perspectives
  • Our Purpose
    • Commitment To Global Health
    • Positions on Health Policies
    • Transparency
    • Contributions & Partnerships
  • Our Products
    • Product Listing
    • How Drugs are Made
    • Distributors
    • Global Product Information Contacts

Footer aside

  • Footer Aside Section1
    • CAREER-SEEKERS
    • INVESTORS
    • News & Media
    • Partners
  • Footer Aside Section 2
    • Healthcare Professionals
    • Business To Business
    • Change Region
    • Sitemap
  • Footer Aside Section3
    • Twitter
    • Facebook
    • Linkedin
    • Instagram
    • Youtube
  • Footer Aside Section4
    • Contact Us
    • Terms of Use
    • Privacy Policy
Pfizer Logo Footer

Copyright © 2002-2021 Pfizer Inc. All rights reserved. This information—including product information—is intended only for residents of the United States.
The products discussed herein may have different labeling in different countries.