You are here
Recent Pfizer Press Releases
Pfizer today announced the recipients of the Advancing Science through Pfizer Investigator Research Exchange (ASPIRE) Breast Cancer Research Awards. Four grants totaling more than $3 million (USD) in funding will be awarded to investigators in the United States (U.S.) to support clinical research projects involving Pfizer compounds in breast cancer.more...
Effective January 1, 2019, Dr. Albert Bourla to become Chief Executive Officer (CEO) and Ian Read to serve as Executive Chairman of the Board of Directors
NEW YORK--(BUSINESS WIRE)--Pfizer Inc. (NYSE:PFE) today announced its Board of Directors has
unanimously elected Dr. Albert Bourla, 56, Pfizer Chief Operating
Officer (COO), to succeed Ian Read as CEO effective January 1, 2019. Ian
Read will transition from his current role as Chairman and CEO to
Executive Chairman of Pfizer’s Board of Directors.
Approval Supported by Data from Phase 3 Head-to-Head Study vs. Gefitinib
NEW YORK--(BUSINESS WIRE)--Pfizer Inc. (NYSE:PFE) today announced that the U.S. Food and Drug
Administration (FDA) has approved VIZIMPRO® [vih-ZIM-pro] (dacomitinib),
a kinase inhibitor for the first-line treatment of patients with
metastatic non-small cell lung cancer (NSCLC) with epidermal growth
factor receptor (EGFR) exon 19 deletion or exon 21 L858R substitution
mutations as detected by an FDA-approved test.
NEW YORK--(BUSINESS WIRE)--The board of directors of Pfizer Inc. today declared a 34-cent
fourth-quarter 2018 dividend on the company’s common stock, payable
December 3, 2018, to shareholders of record at the close of business on
November 9, 2018. The third-quarter 2018 cash dividend will be the 320th
consecutive quarterly dividend paid by Pfizer.
Breakthrough Therapy Designation Designed by FDA to Expedite the Development and Review of Drugs and Vaccines Which May Demonstrate Substantial Improvement Over Available Therapy 1
NEW YORK--(BUSINESS WIRE)--Pfizer Inc. (NYSE:PFE) announced today that its 20-Valent Pneumococcal
Conjugate Vaccine (20vPnC) candidate, PF-06482077, received Breakthrough
Therapy designation from the US Food and Drug Administration (FDA) for
the prevention of invasive disease and pneumonia caused by Streptococcus
pneumoniae serotypes in the vaccine in adults aged 18 years and older.2
Pfizer expects to start Phase 3 trials in a few months.
Pfizer Inc. invites investors and the general public to view and listen
to a webcast of a conference call with investment analysts at 10 a.m.
EDT on Tuesday, October 30, 2018. The purpose of the call is to provide
an update on Pfizer’s results, as reflected in the company’s Third
Quarter 2018 Performance Report, to be issued that morning.
—Findings from sensitivity and post-hoc analyses were presented during a Late Breaking Clinical Trials Session at the Heart Failure Society of America 22 nd Annual Scientific Meeting— —Results of new analyses of all-cause mortality favored tafamidis across all sub-groups— —29% and 31% reduction in the risk of death observed in wild-type and hereditary sub-groups, respectively—
NEW YORK--(BUSINESS WIRE)--Pfizer Inc. (NYSE:PFE) announced today that additional sensitivity and
post-hoc analyses from the Tafamidis Phase 3 Transthyretin Amyloid
Cardiomyopathy (ATTR-ACT) study provide further detail on the effect of
tafamidis across wild-type, hereditary, and New York Heart Association
(NYHA) class sub-groups of patients with transthyretin amyloid
cardiomyopathy (ATTR-CM).1 Tafamidis is the only
investigational treatment that has completed a Phase 3 trial evaluating
its safety and efficacy for the treatment of ATTR-CM.1
ATTR-CM is a rare, fatal, and underdiagnosed condition associated with
progressive heart failure for which there are currently no approved
Pfizer Inc. (NYSE:PFE) today announced results from its Phase 2a study
of PF-06651600, an oral Janus kinase (JAK) 3 inhibitor, and PF-06700841,
a tyrosine kinase (TYK) 2/JAK1 inhibitor, compared to placebo, in
patients with moderate to severe alopecia areata (AA), an autoimmune
disease characterized by hair loss and often associated with profound
psychological consequences. Both JAK inhibitors met the primary efficacy
endpoint in improving hair regrowth on the scalp relative to baseline at
week 24 (33.6 points and 49.5 points for JAK3 and TYK2/JAK1,
respectively) as measured by the Severity of Alopecia Tool (SALT) score
(100 point scale). The findings were presented during a Late-Breaking
News session at the 27th European Academy of Dermatology and Venereology
(EADV) Congress in Paris, France.
- First positive Phase III immunotherapy trial in combination with a tyrosine kinase inhibitor (TKI) in any tumor type
- Results significant in both PDL1+ and all-comer populations
- Alliance plans to pursue a regulatory submission in the US and discussions with other health authorities based on interim results for progression-free survival
- Trial will continue for the other primary endpoint of overall survival; detailed results to be submitted for presentation at an upcoming medical congress
Merck KGaA, Darmstadt, Germany, and Pfizer Inc. (NYSE: PFE) today announced positive top-line results from the pivotal Phase III JAVELIN Renal 101 study evaluating BAVENCIO® (avelumab) in combination with INLYTA® (axitinib), compared with SUTENT® (sunitinib) as initial therapy for patients with advanced renal cell carcinoma (RCC).more...
Pfizer Inc. invites investors and the general public to listen to a
webcast of a discussion with Frank D’Amelio, Executive Vice President,
Business Operations, and Chief Financial Officer, at the Morgan Stanley
16th Annual Global Healthcare Conference on Thursday,
September 13, 2018 at 2:55 p.m. Eastern Daylight Time.
Phase II data accepted for late-breaker news session at 2018 EADV Congress
NEW YORK--(BUSINESS WIRE)--Pfizer Inc. (NYSE:PFE) today announced its investigational oral Janus
kinase 3 (JAK3) inhibitor PF-06651600 received Breakthrough
Therapy designation from the U.S. Food and Drug Administration (FDA) for
the treatment of patients with alopecia areata, a chronic autoimmune
skin disease that causes hair loss on the scalp, face, or body.1,2
NEW YORK--(BUSINESS WIRE)--Pfizer Inc. (NYSE: PFE) announced today that it is terminating two
ongoing clinical studies evaluating domagrozumab (PF-06252616) for the
treatment of Duchenne muscular dystrophy (DMD): a Phase 2 safety and
efficacy study (B5161002) and an open-label extension study (B5161004).
The Phase 2 study (B5161002), did not meet its primary efficacy
endpoint, which was to demonstrate a difference in the mean change from
baseline in 4 Stair Climb (in seconds) following one year of treatment
with domagrozumab as compared to placebo in patients with DMD. Further
evaluation of the totality of evidence including secondary endpoints did
not support a significant treatment effect. The decision comes after a
thorough review of data available at the time of the primary analysis,
which evaluated all study participants after one year of treatment, as
well as those participants who were in the trial beyond one year. The
studies were not terminated for safety reasons. Pfizer will continue to
review the data to better understand any insights they may provide, and
will share results with the scientific and patient community.
ATTR-ACT Showed that Tafamidis Significantly Reduced the Combination of All-cause Mortality and Cardiovascular-related Hospitalizations Data Showed a 30% Reduction in the Risk of Mortality and 32% Reduction in the Rate of Cardiovascular-related Hospitalizations with Tafamidis in People with Transthyretin Amyloid Cardiomyopathy versus Placebo
NEW YORK--(BUSINESS WIRE)--Pfizer Inc. (NYSE:PFE) announced today the primary results from the
Tafamidis Phase 3 Transthyretin Cardiomyopathy (ATTR-ACT) study, which
showed tafamidis significantly reduced the hierarchical combination of
both all-cause mortality and frequency of cardiovascular-related
hospitalizations compared to placebo over a 30-month period (P=0.0006)
in patients with wild-type or variant (hereditary) transthyretin amyloid
cardiomyopathy (ATTR-CM).1 ATTR-CM is a rare, fatal, and
underdiagnosed condition associated with progressive heart failure for
which there are no approved pharmacologic treatments.2,3
Amendments accelerate anticipated primary completion dates for both ARCHES and EMBARK trials
NEW YORK & TOKYO--(BUSINESS WIRE)--Pfizer Inc. (NYSE:PFE) and Astellas Pharma Inc. (TSE:4503, President and
CEO: Kenji Yasukawa, Ph.D., “Astellas”) today announced amendments to
the protocols for two registrational Phase 3 trials, ARCHES and EMBARK,
designed to evaluate the safety and efficacy of XTANDI®
(enzalutamide) in men with hormone-sensitive prostate cancer (HSPC).
These amendments accelerate timelines for the anticipated primary
completion dates of both trials.
Pfizer Inc. invites investors and the general public to view and listen to a webcast of a conference call with investment analysts on Monday, August 27, 2018 at 9:00 a.m. EDT. The purpose of the call is to review the Tafamidis data presentation at the ESC Congress 2018 organized by the European Society of Cardiology.more...
Pfizer Inc. (NYSE:PFE) announced today that the European Commission (EC) has approved XELJANZ® (tofacitinib citrate) 10 mg twice-daily (BID) for at least eight weeks, followed by XELJANZ 5 mg BID or 10 mg BID, for the treatment of adult patients with moderately to severely active ulcerative colitis (UC) who have had an inadequate response, lost response, or were intolerant to either conventional therapy or a biologic agent.1 XELJANZ is the first and only oral therapy and Janus kinase (JAK) inhibitor to be approved for this patient population.more...
Second-Quarter 2018 Revenues of $13.5 Billion, Reflecting 2% Operational Growth Second-Quarter 2018 Reported Diluted EPS(1) of $0.65, Adjusted Diluted EPS(2) of $0.81 Raised 2018 Financial Guidance for Adjusted Diluted EPS(2) by $0.05 to a Range of $2.95 to $3.05 Lowered Midpoint of 2018 Revenue Guidance Range by $500 Million Solely to Reflect Recent Unfavorable Changes in Foreign Exchange Rates
Pfizer Inc. (NYSE: PFE) reported financial results for second-quarter 2018 and raised 2018 financial guidance for Adjusted diluted EPS(2).more...
The European Commission decision marks the approval of Pfizer’s first therapeutic oncology biosimilar
Pfizer Inc. (NYSE:PFE) today announced the European Commission (EC) has approved TRAZIMERA™,1 a biosimilar to Herceptin®* (trastuzumab), for the treatment of human epidermal growth factor (HER2) overexpressing breast cancer and HER2 overexpressing metastatic gastric or gastroesophageal junction adenocarcinoma.2 This approval follows the recommendation from the Committee for Medicinal Products for Human Use in May 2018.1more...