The Endocrine Unit of the University Hospital of Messina is seeking support for developing a spoke to hub interactive network designed to improve healthcare professionals’ (HCPs) knowledge on growth hormone deficiency (GHD) diagnosis, management and long-term follow-up, aiming to increase GHD cases identification and improve rGH treatment adherence. A network between our tertiary referral center and General Practitioners of GHD patients (GPs) as well as other HCPs (Outpatient Clinic Endocrinologists, Neurosurgeons, Neuroradiologists, Neuro-oncologists) practicing in Sicily and Calabria will be established. All participants will attend “GHD management” training workshops. Moreover, we seek to develop a website/webapp featuring all necessary information on GHD diagnosis, treatment and long term follow-up also including a live-chat allowing prompt contact between spokes and the hub unit. Our goals are to increase GHD diagnosis, improve HCPs GHD patient management skills, aiming to increase medication adherence, patient quality of life and to reduce therapy drop-out.