Area:
Dermatology

Evidence-Based Evaluation of Antibiotic Drug Allergy in the Inpatient Setting

Organization:
Perelman School of Medicine, University of Pennsylvania, Department of Dermatology

This pilot study addresses a significant practice gap in the management of purported penicillin allergy in hospitalized patients.  Up to 90% of listed penicillin allergies are invalid; prior data suggest such patients have longer hospital stays, higher rates of resistant nosocomial infections, greater healthcare utilization, and even higher mortality; and a validated and reliable testing method exists; yet, no interventional testing protocol has been implemented on a large scale for inpatient testing.  In this study, we will test the feasibility and impact of implementing evidence-based penicillin allergy testing guidelines on a hospital-wide level among patients admitted to our hospital with penicillin allergy.  Demonstrable improvements in utilization of broad-spectrum antibiotics, healthcare cost, nosocomial infections, length of stay, mortality, and other metrics as a result of this pilot study may enable implementation of this protocol as an ongoing quality improvement measure at our institution and other major health systems.

Approval Date:
November 2017
Amount Awarded:
$19,999.00
Start Date:
01/01/2018
End Date:
06/30/2018
Status:
In Progress
RFP:
Dermatology Early Career Investigator QI RFP
RFP ID:
2017DERM3