- Hospitalized/chronic care pediatric patients (birth through 17 years)
- Known infections due to vancomycin-resistant enterococcus species, including diagnosis
of hospital-acquired pneumonia, complicated skin and skin structure infections,
catheter-related bacteremia, bacteremia of unidentified source, and other infections
- Requires a minimum of 3 days of IV medication
- Patients with mixed infections due to VRE & gram negative bacteria are allowed to
enroll in the study. For most of the infections, 2 or more of additional symptoms are
required.
Exclusion Criteria:
- Potentially effective concomitant antibiotic
- A high surgical cure rate
- Medical conditions which would preclude clinical evaluation or require treatment of
longer duration than 28 days
- 24 hours of antibiotic treatment within 48 hours of study entry (unless pre-approved)
- Having an infected device that could not be removed
further examination by the investigator is necessary.