- Idiopathic Parkinson's disease
- Modified Hoehn and Yahr Scale Stages 1-4
- Age over 30 years
- Previous participation in prior sumanirole studies
- Use of dopamine agonist medications and other medications in defined timeframe
- Unstable dose of CNS active therapies (eg, hypnotics, antidepressants, anxiolytics)
within the last 30 days
- Atypical Parkinson's syndromes due to drugs, metabolic disorders, encephalitis, or
degenerative diseases
- Dementia
- History of active epilepsy within the past year
- Significant liver disease with defined laboratory criteria
- Significant renal disease with defined laboratory criteria
- Certain cardiac conditions
- Electroconvulsive therapy in the previous 90 days
- Subjects participating in other drug studies or receiving other investigational drugs
within previous 30 days
- Positive pregnancy test at Screen
- Unwillingness to use adequate contraceptive methods
- Lactating women
- History of stereotaxic brain surgery
- Malignant melanoma or history of treated melanoma