Anti-angiogenesis Agent AG-013736 in Patients With Metastatic Renal Cell Carcinoma
NCT00076011
ABOUT THIS STUDY
FOR MORE INFORMATION
Contact a representative by phone, email, or visiting the study website. Please see the references below:
Pfizer Clinical Trials Contact Center
1-800-718-1021
- Histologically documented RCC with metastases.
- Failure of 1 prior cytokine-based therapy (interleukin-2 and/or interferon) due to disease progression or unacceptable treatment-related toxicity
- Any prior systemic treatment for Renal Cell Carcinoma [RCC] other than 1 prior
cytokine-based treatment regimen. Cytokine-based regimens containing thalidomide or an
anti-angiogenesis agent are not allowed.
- Inability to take oral medication
NEED INFO?
Questions about a trial? Call or email to reach a Pfizer Clinical Trial Contact Center Representative
TRY A NEW SEARCH
Search for Clinical Trials by condition, keyword or trial number. Share your location or enter your city or zip code to find studies near you.
Based on your search, you may also be interested in
- Sollentuna,
- Burbank, California
- Burbank, California
- Downey, California
- Glendale, California
- Los Angeles, California
- Los Angeles, California
- Los Angeles, California
- Los Angeles, California
- Los Angeles, California
- Los Angeles, California
- Los Angeles, California
- Montebello, California
- West Covina, California
- Whittier, California
- Aurora, Colorado
- Aurora, Colorado
- Aurora, Colorado
- Boulder, Colorado
- Colorado Springs, Colorado
- Denver, Colorado
- Denver, Colorado
- Lakewood, Colorado
- Littleton, Colorado
- Lone Tree, Colorado
- Longmont, Colorado
- Parker, Colorado
- Thornton, Colorado
- Washington, District of Columbia
- Washington, District of Columbia
- Bonita Springs, Florida
- Bradenton, Florida
- Cape Coral, Florida
- Cape Coral, Florida
- Deerfield Beach, Florida
- Englewood, Florida
- Fort Myers, Florida
- Fort Myers, Florida
- Fort Myers, Florida
- Fort Myers, Florida
- Miami, Florida
- Naples, Florida
- Naples, Florida
- Orlando, Florida
- Orlando, Florida
- Port Charlotte, Florida
- Sarasota, Florida
- Sarasota, Florida
- Venice, Florida
- Venice, Florida
- Atlanta, Georgia
- Ringgold, Georgia
- Boise, Idaho
- Fruitland, Idaho
- Meridian, Idaho
- Nampa, Idaho
- Twin Falls, Idaho
- Maywood, Illinois
- Carmel, Indiana
- Fishers, Indiana
- Greenfield, Indiana
- Indianapolis, Indiana
- Indianapolis, Indiana
- Boston, Massachusetts
- Boston, Massachusetts
- Ann Arbor, Michigan
- Detroit, Michigan
- Farmington Hills, Michigan
- Minneapolis, Minnesota
- Columbia, Missouri
- Saint Louis, Missouri
- Saint Louis, Missouri
- Washington, Missouri
- Henderson, Nevada
- Las Vegas, Nevada
- Las Vegas, Nevada
- Las Vegas, Nevada
- Las Vegas, Nevada
- Hackensack, New Jersey
- Hackensack, New Jersey
- Hackensack, New Jersey
- Bronx, New York
- New York, New York
- New York, New York
- Oneida, New York
- Oswego, New York
- Syracuse, New York
- Syracuse, New York
- Cary, North Carolina
- Durham, North Carolina
- Durham, North Carolina
- Elizabeth City, North Carolina
- Elizabeth City, North Carolina
- Raleigh, North Carolina
- Cleveland, Ohio
- Cleveland, Ohio
- Columbus, Ohio
- Columbus, Ohio
- Columbus, Ohio
- Mayfield Heights, Ohio
- Mentor, Ohio
- Orange Village, Ohio
- Westlake, Ohio
- Eugene, Oregon
- Springfield, Oregon
- Hershey, Pennsylvania
- Philadelphia, Pennsylvania
- Charleston, South Carolina
- Easley, South Carolina
- Greenville, South Carolina
- Greenville, South Carolina
- Seneca, South Carolina
- Spartanburg, South Carolina
- Chattanooga, Tennessee
- Chattanooga, Tennessee
- Franklin, Tennessee
- Franklin, Tennessee
- Gallatin, Tennessee
- Hermitage, Tennessee
- Hixson, Tennessee
- Lebanon, Tennessee
- Murfreesboro, Tennessee
- Nashville, Tennessee
- Nashville, Tennessee
- Nashville, Tennessee
- Nashville, Tennessee
- Nashville, Tennessee
- Nashville, Tennessee
- Nashville, Tennessee
- Smyrna, Tennessee
- Austin, Texas
- Austin, Texas
- Austin, Texas
- Austin, Texas
- Austin, Texas
- Austin, Texas
- Bedford, Texas
- Cedar Park, Texas
- Dallas, Texas
- Fort Worth, Texas
- Fort Worth, Texas
- Fort Worth, Texas
- Houston, Texas
- Houston, Texas
- Round Rock, Texas
- Round Rock, Texas
- Tyler, Texas
- Webster, Texas
- Webster, Texas
- Arlington, Virginia
- Chesapeake, Virginia
- Fairfax, Virginia
- Gainesville, Virginia
- Hampton, Virginia
- Leesburg, Virginia
- Newport News, Virginia
- Norfolk, Virginia
- Virginia Beach, Virginia
- Woodbridge, Virginia
- Seattle, Washington
- Seattle, Washington
- Seattle, Washington
- Garran, Australian Capital Territory
- Kurralta Park, South Australia
- Ballarat, Victoria
- East Melbourne, Victoria
- Heidelberg West, Victoria
- Heidelberg, Victoria
- Wien,
- Wien,
- Rio de Janeiro, RJ
- Porto Alegre, RS
- Barretos, SP
- Sao Paulo, SP
- Calgary, Alberta
- Edmonton, Alberta
- Kelowna, British Columbia
- Moncton, New Brunswick
- St. John's, Newfoundland and Labrador
- Oshawa, Ontario
- Beijing, Chaoyang District
- Nanjing, Jiangsu
- Beijing, P.R.
- Xi'an, Shaanxi
- Guangzhou,
- Shanghai,
- Tianjin,
- Lyon, Cedex 08
- Bordeaux Cedex,
- CRETEIL Cedex,
- Marseille Cedex 09,
- Paris Cedex 15,
- Rennes,
- St Herblain Cedex,
- Tours Cedex 1,
- Vandoeuvre les Nancy,
- Villejuif Cedex,
- Aachen,
- Berlin,
- Essen,
- Hannover,
- Mainz,
- Muenchen,
- Oldenburg,
- Athens, Attiki
- Thessaloniki, Macedonia
- Gurgaon, Haryana
- Kochi, Kerala
- Mumbai, Maharashtra
- Ludhiana, Punjab
- Jaipur, Rajasthan
- Dublin 24,
- Arezzo,
- Aviano (PN),
- Aviano (PN),
- Brescia,
- Cremona,
- Genova,
- Milano,
- Napoli,
- Napoli,
- Padova,
- Pavia,
- Roma,
- Roma,
- Rozzano (MI),
- Sapporo-shi, Hokkaido
- Sapporo, Hokkaido
- Tsukuba, Ibaraki
- Osakasayama, Osaka
- Hamamatsu-City, Shizuoka
- Sunto-gun, Shizuoka
- Arakawa-ku, Tokyo
- Chuo-Ku, Tokyo
- Itabashi-ku, Tokyo
- Shinjuku-ku, Tokyo
- Shinjuku-ku, Tokyo
- Ube-shi, Yamaguchi
- Akita,
- Chiba,
- Fukuoka,
- Kumamoto,
- Tokushima,
- Yamagata,
- Goyang-si, Gyeonggi-do
- Busan,
- Seoul,
- Seoul,
- Seoul,
- Seoul,
- Poznan, Wielkopolska
- Poznan, Wielkopolska
- Gdansk,
- Poznan,
- Poznan,
- Warszawa,
- Wroclaw,
- Obninsk, Kaluga Region
- Moscow,
- Moscow,
- Moscow,
- Moscow,
- Moscow,
- St. Petersburg,
- Singapore,
- Bratislava,
- Bratislava,
- Zilina,
- L'hospitalet de Llobregat, Barcelona
- Pamplona, Navarra
- Pamplona, Navarra
- Barcelona,
- Madrid,
- Madrid,
- Malaga,
- Sevilla,
- Zaragoza,
- Linkoping,
- Umea,
- Vaxjo,
- Kaohsiung Hsien,
- Taichung,
- Taipei,
- Taoyuan,
- London, England
- Northwood, Middlesex
- Bebington, Wirral,
- Birmingham,
- Bournemouth,
- Bristol,
- Cambridge,
- Glasgow,
- London,
- Oxford,
- Surrey,
- Los Angeles, California
- Mission Hills, California
- Monterey Park, California
- Northridge, California
- San Francisco, California
- San Francisco, California
- Boston, Massachusetts
- Boston, Massachusetts
- Ann Arbor, Michigan
- Henderson, Nevada
- Las Vegas, Nevada
- Las Vegas, Nevada
- New York, New York
- Philadelphia, Pennsylvania
- Madison, Wisconsin
- Miami, Florida
- Miami, Florida
- Arlington Heights, Illinois
- Niles, Illinois
- Carmel, Indiana
- Fishers, Indiana
- Greenfield, Indiana
- Indianapolis, Indiana
- Indianapolis, Indiana
- Columbia, Missouri
- Omaha, Nebraska
- Henderson, Nevada
- Henderson, Nevada
- Henderson, Nevada
- Las Vegas, Nevada
- Las Vegas, Nevada
- Las Vegas, Nevada
- Morristown, New Jersey
- Parsippany, New Jersey
- Albany, New York
- Albany, New York
- Latham, New York
- Rexford, New York
- Troy, New York
- Cary, North Carolina
- Raleigh, North Carolina
- Raleigh, North Carolina
- Portland, Oregon
- Portland, Oregon
- Portland, Oregon
- Tualatin, Oregon
- Hershey, Pennsylvania
- Charleston, South Carolina
- Charleston, South Carolina
- Amarillo, Texas
- Beaumont, Texas
- Bedford, Texas
- Dallas, Texas
- Fort Worth, Texas
- Fort Worth, Texas
- Fort Worth, Texas
- Fort Worth, Texas
- Grapevine, Texas
- Kerrville, Texas
- McAllen, Texas
- Midland, Texas
- San Antonio, Texas
- San Antonio, Texas
- Webster, Texas
- Weslaco, Texas
- Christiansburg, Virginia
- Low Moor, Virginia
- Roanoke, Virginia
- Salem, Virginia
- Wytheville, Virginia
- Vancouver, Washington
- Vancouver, Washington
- Wenatchee, Washington
- Banja Luka,
- Sarajevo,
- Tuzla,
- Sofia,
- Varna,
- Temuco, Cautin
- Temuco, IX Region
- Providencia, Santiago
- Santiago,
- Beijing, Beijing
- Haidian District, Beijing
- Fuzhou, Fujian
- Guangzhou, Guang DONG
- Guangzhou, Guangdong
- Nanjing, Jiangsu
- Nanjing, Jiangsu
- Changchun, Jilin
- Shen Yang, LIAO NING
- Xi'an, Shaanxi
- Shanghai, Shanghai
- Chengdu, Sichuan
- Hangzhou, Zhejiang
- Beijing,
- Beijing,
- Chongqing,
- Nanjing,
- Shanghai,
- Tianjin,
- Tianjin,
- Hyderabad, Andhra Pradesh
- Bangalore, Karnataka
- Bangalore, Karnataka
- Bangalore, Karnataka
- Nagpur, Maharashtra
- Nashik, Maharashtra
- Nashik, Maharashtra
- Pune, Maharashtra
- Pune, Maharashtra
- Bangalore,
- Kuala Lumpur,
- Mexico, DF
- Mexico City, Distrito Federal
- Toluca, Estado DE Mexico
- Aguascalientes,
- Oaxaca,
- Quezon City, Diliman
- Quezon City, Metro Manila
- Quezon City, Metro Manila
- Makati City,
- Manila,
- Timisoara, JUD. Timis
- Cluj-Napoca,
- Cluj-Napoca,
- Moscow,
- Moscow,
- Ryazan,
- Ryazan,
- Saint-Petersburg,
- Ufa,
- Port Elizabeth,
- Taichung,
- Taipei,
- Dnipropetrovsk,
- Kharkiv,
- Kyiv,
- Lviv,
- Zaporizhzhya,
Descriptive Information | ||||
---|---|---|---|---|
Brief Title ICMJE | Anti-angiogenesis Agent AG-013736 in Patients With Metastatic Renal Cell Carcinoma | |||
Official Title ICMJE | Phase 2 Study of AG 013736 as Second-Line Treatment in Patients With Metastatic Renal Cell Cancer | |||
Brief Summary | The primary purpose of this protocol is to determine the activity of AG 013736 in patients with metastatic renal cell cancer who have received 1 prior cytokine-based therapy. | |||
Detailed Description | Not Provided | |||
Study Type ICMJE | Interventional | |||
Study Phase ICMJE | Phase 2 | |||
Study Design ICMJE | Allocation: Non-Randomized Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Treatment | |||
Condition ICMJE | Kidney Neoplasms | |||
Intervention ICMJE | Drug: Vascular Endothelial Growth Factor Receptor [VEGFR] and Platelet-Derived Growth Factor Receptor [PDGFR] inhibitor | |||
Study Arms ICMJE | Not Provided | |||
Publications * | Rixe O, Bukowski RM, Michaelson MD, Wilding G, Hudes GR, Bolte O, Motzer RJ, Bycott P, Liau KF, Freddo J, Trask PC, Kim S, Rini BI. Axitinib treatment in patients with cytokine-refractory metastatic renal-cell cancer: a phase II study. Lancet Oncol. 2007 Nov;8(11):975-84. Epub 2007 Oct 23. | |||
* Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline. | ||||
Recruitment Information | ||||
Recruitment Status ICMJE | Completed | |||
Actual Enrollment ICMJE | 52 | |||
Original Enrollment ICMJE | Same as current | |||
Actual Study Completion Date ICMJE | February 2007 | |||
Actual Primary Completion Date | February 2007 (Final data collection date for primary outcome measure) | |||
Eligibility Criteria ICMJE | Inclusion Criteria:
Exclusion Criteria:
| |||
Sex/Gender ICMJE |
| |||
Ages ICMJE | 18 Years and older (Adult, Older Adult) | |||
Accepts Healthy Volunteers ICMJE | No | |||
Contacts ICMJE | Contact information is only displayed when the study is recruiting subjects | |||
Listed Location Countries ICMJE | France, Germany, United States | |||
Removed Location Countries | ||||
Administrative Information | ||||
NCT Number ICMJE | NCT00076011 | |||
Other Study ID Numbers ICMJE | A4061012 | |||
Has Data Monitoring Committee | Not Provided | |||
U.S. FDA-regulated Product | Not Provided | |||
IPD Sharing Statement ICMJE | Not Provided | |||
Responsible Party | Pfizer | |||
Study Sponsor ICMJE | Pfizer | |||
Collaborators ICMJE | Not Provided | |||
Investigators ICMJE |
| |||
PRS Account | Pfizer | |||
Verification Date | June 2012 | |||
ICMJE Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP |