You are here

Azithromycin in Combination With Chloroquine Versus Chloroquine in the Eradication of Asymptomatic Plasmodium Falciparum

Last updated on February 20, 2019

FOR MORE INFORMATION
Study Location
Contact
1-800-718-1021
Eligibility criteria
Condition
The disease, disorder, syndrome, illness, or injury that is being studied.
Falciparum Malaria
Sex
Females and Males
Age
Pediatric Trials: 0-17 Years
Adult Trials: 18+ Years
18-60 years
Inclusion criteria
The factors, or reasons, that allow a person to participate in a clinical study.
Show details

- Healthy adult: male or female

- Asymptomatic mono-infection with P. falciparum parasitemia with a parasite density of
1000 - 30,000 parasites/μL

- Age 18 years to 60 years

- Willingness to sign and ability to understand consent form

- Willingness and ability to return for scheduled follow up visits

Exclusion criteria
The factors, or reasons, that prevent a person from participating in a clinical study.
Show details

- Mixed malaria infection by Giemsa smear

- History of allergy to or hypersensitivity to chloroquine, Azithromycin or other
macrolides (e.g. erythromycin, clarithromycin)

- Any of the following: a.) Antimalarial therapy administered in the past 4 weeks,
including quinine therapy or an artemisinin derivative; or b.) An antibacterial with
known antimalarial activity (including, erythromycin, doxycycline, clindamycin,
cotrimoxazole) within one week prior to enrollment into the study

- Fever, history of fever in past 48 hours, or signs/symptoms of malaria (including
acute or subacute headache, nausea, or vomiting)

- Inability to swallow oral medication

- Laboratory evidence or history of significant cardiovascular, liver, hematologic or
renal functional abnormality

- Any situation which could prevent the patient from returning to follow up visits

- Pregnancy or breast feeding

- Any other concurrent illness that may confound the result

- Any other condition or circumstance that in the opinion of the Investigator may pose a
threat to the study participant or study

NCT00082563
Pfizer
Terminated
Azithromycin in Combination With Chloroquine Versus Chloroquine in the Eradication of Asymptomatic Plasmodium Falciparum

NEED INFO?

Questions about a trial? Call or email to reach a Pfizer Clinical Trial Contact Center

Pfizer Clinical Trials Contact Center

1-800-718-1021

[email protected]

call now

Try a new search

Search for Clinical Trials by condition, keyword or trial number. Share your location or enter your city or zip code to find studies near you.

FOR MORE INFORMATION

Contact a representative by phone, email, or visiting the study website. Please see the references below:

BY PHONE

Pfizer Clinical Trials Contact Center

1-800-718-1021

BY EMAIL

Contact

[email protected]

Call Now