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The Purpose of This Study is to Determine if Eplerenone is Effective in Treatment of Mild to Moderate Heart Failure

Last updated on February 23, 2019

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Study Location
Pfizer Investigational Site
Castro Valley, California, 94546 United States
Contact
1-800-718-1021
Eligibility criteria
Condition
The disease, disorder, syndrome, illness, or injury that is being studied.
Congestive Heart Failure
Sex
Females and Males
Age
Pediatric Trials: 0-17 Years
Adult Trials: 18+ Years
21 + years
Inclusion criteria
The factors, or reasons, that allow a person to participate in a clinical study.
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- Current symptoms consistent with mild to moderate heart failure (NYHA functional class
II and III)

- LVEF (left ventricular ejection fraction) of screening

- Therapy with an angiotensin converting enzyme inhibitor (ACEI) or angiotensin receptor
blocker (ARB) and beta-blocker (BB) (unless documented intolerance) for at least 3
months duration and at dose that has not been adjusted within the previous 4 weeks

Exclusion criteria
The factors, or reasons, that prevent a person from participating in a clinical study.
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- Current decompensated heart failure or heart failure hospitalization or severe heart
failure (NYHA functional class IV) within 6 months of screening

- Use of eplerenone or spironolactone within 30 days of randomization or for more than 7
days within the previous 6 months

NCT00082589
Pfizer
Completed
The Purpose of This Study is to Determine if Eplerenone is Effective in Treatment of Mild to Moderate Heart Failure

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