Eligibility criteria
Condition
Hemophilia B
Sex
Females and Males
Age
12 + years
Inclusion criteria
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- Moderate to severe hemophilia B (FIX: C ≤2%)
- Previously treated patients (PTPs) with ≥150 documented exposure days
- Age ≥ 12 years (US sites only)
Exclusion criteria
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- Detectable factor IX inhibitor defined as ?0.6 Bethesda Units for pooled plasma
reported by the local laboratory (family history of inhibitors will not exclude the
patient)
- Patient history of factor IX inhibitor replacement therapy
- Patient unable to be off factor IX replacement therapy for at least 5 days without
bleeding