Eligibility criteria
Condition
Rheumatoid Arthritis
Sex
Females and Males
Age
18-75 years
Inclusion criteria
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- Meet American College of Rheumatology (ACR) criteria for RA
- Have active RA
- Disease duration of at least 6 months
- Disease onset at > 16 years of age.
Exclusion criteria
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- Any prior use of anti-TNF alpha biologics, rituximab, receipt of anti-CD4 or
diphtheria interleukin-2 fusion protein or other immunosuppressive biologics (except
for anakinra)
- Largely or wholly incapacitated with the subject bedridden or confined to a
wheelchair, permitting limited or no self-care
- Pregnant or breastfeeding women or women planning to become pregnant during the study
or within 12 weeks after the last dose of test article