- Age 30 to 79 years old
- Triglyceride level 6.8 mmol/L at screening
- LDL-C of 5.7 mmol/L at screening
- Pregnant or lactating women, or women of childbearing potential not using an
acceptable method of contraception. The latter are defined as: abstinence, surgical
sterilization, oral contraceptives for at least 3 cycles, intrauterine device,
implant, depot injection, or barrier method in conjunction with contraceptive foam or
jelly.
- Subjects whose blood cholesterol levels are controlled (LDL-C targets) with statins
other than atorvastatin
- Subjects receiving statin doses higher than the following: 10-40mg for simvastatin ,
20-40mg for fluvastatin, pravastatin and lovastatin and 10-20 mg for rosuvastatin.
Subjects already treated with atorvastatin at the time of screening are not eligible
unless atorvastatin has been discontinued at least 2 months prior to screening
- Subjects receiving 2 or more lipid lowering agents are excluded (statins + resins or
fibrates or niacin or fish oils)