Study Evaluating SRA-333 in Mild to Moderate Alzheimer's Disease (AD)
NCT00151333
ABOUT THIS STUDY
FOR MORE INFORMATION
Contact a representative by phone, email, or visiting the study website. Please see the references below:
Pfizer Clinical Trials Contact Center
1-800-718-1021
- Diagnosis of probable AD according to the NINCDS-ADRDA criteria.
- Men and postmenopausal or surgically sterile women aged from 50 to 85 inclusive.
- Able to give informed consent. Patient's caregiver must consent to participate in the study.
- Significant neurologic disease other than AD that may affect cognition.
- Current clinically significant systemic illness which is likely to deteriorate or
affect the subject's safety during the study.
Other exclusions apply
NEED INFO?
Questions about a trial? Call or email to reach a Pfizer Clinical Trial Contact Center Representative
TRY A NEW SEARCH
Search for Clinical Trials by condition, keyword or trial number. Share your location or enter your city or zip code to find studies near you.
Based on your search, you may also be interested in
- Birmingham, Alabama
- Goodyear, Arizona
- Phoenix, Arizona
- Phoenix, Arizona
- Sun City, Arizona
- Tucson, Arizona
- Tucson, Arizona
- Little Rock, Arkansas
- Berkeley, California
- Carson, California
- Costa Mesa, California
- Encino, California
- Fresno, California
- Fullerton, California
- Glendale, California
- Imperial, California
- La Jolla, California
- La Jolla, California
- Laguna Hills, California
- Long Beach, California
- Los Alamitos, California
- Los Angeles, California
- Los Angeles, California
- National City, California
- Newport Beach, California
- Oceanside, California
- Orange, California
- Pasadena, California
- Rancho Mirage, California
- Sacramento, California
- Sacramento, California
- San Diego, California
- San Diego, California
- San Francisco, California
- San Francisco, California
- Santa Ana, California
- Santa Monica, California
- Sherman Oaks, California
- Walnut Creek, California
- Boulder, Colorado
- Denver, Colorado
- Fort Collins, Colorado
- Danbury, Connecticut
- Fairfield, Connecticut
- New Haven, Connecticut
- New Haven, Connecticut
- Norwalk, Connecticut
- Waterbury, Connecticut
- Newark, Delaware
- Washington, District of Columbia
- Atlantis, Florida
- Bradenton, Florida
- Deerfield Beach, Florida
- Delray Beach, Florida
- Fort Lauderdale, Florida
- Fort Myers, Florida
- Fort Walton Beach, Florida
- Ft. Myers, Florida
- Hallandale Beach, Florida
- Hollywood, Florida
- Jacksonville, Florida
- Maitland, Florida
- Melbourne, Florida
- Miami, Florida
- Miami, Florida
- Miami, Florida
- Ocala, Florida
- Orange City, Florida
- Orlando, Florida
- Palm Beach Gardens, Florida
- Pembroke Pines, Florida
- Port Charlotte, Florida
- Sarasota, Florida
- South Miami, Florida
- St Petersburg, Florida
- St. Petersburg, Florida
- Tampa, Florida
- Tampa, Florida
- Tampa, Florida
- Tampa, Florida
- West Palm Beach, Florida
- Atlanta, Georgia
- Atlanta, Georgia
- Atlanta, Georgia
- Columbus, Georgia
- Decatur, Georgia
- Lawrenceville, Georgia
- Chicago, Illinois
- Chicago, Illinois
- Elk Grove Village, Illinois
- Peoria, Illinois
- Springfield, Illinois
- Elkhart, Indiana
- Fort Wayne, Indiana
- Indianapolis, Indiana
- Kansas City, Kansas
- Kansas City, Kansas
- Lenexa, Kansas
- Lexington, Kentucky
- Lexington, Kentucky
- Paducah, Kentucky
- Lake Charles, Louisiana
- New Orleans, Louisiana
- Shreveport, Louisiana
- Shreveport, Louisiana
- Scarborough, Maine
- Baltimore, Maryland
- Baltimore, Maryland
- Rockville, Maryland
- Belmont, Massachusetts
- Boston, Massachusetts
- Boston, Massachusetts
- Haverhill, Massachusetts
- Newton, Massachusetts
- Pittsfield, Massachusetts
- Plymouth, Massachusetts
- Springfield, Massachusetts
- Springfield, Massachusetts
- Weymouth, Massachusetts
- Ann Arbor, Michigan
- Detroit, Michigan
- East Lansing, Michigan
- Grand Rapids, Michigan
- Kalamazoo, Michigan
- Rochester, Minnesota
- Flowood, Mississippi
- Hattiesburg, Mississippi
- Kansas City, Missouri
- Kansas City, Missouri
- St. Louis, Missouri
- St. Louis, Missouri
- Billings, Montana
- Great Falls, Montana
- Omaha, Nebraska
- Las Vegas, Nevada
- Dover, New Hampshire
- Lebanon, New Hampshire
- Berlin, New Jersey
- Eatontown, New Jersey
- Manchester, New Jersey
- Mount Arlington, New Jersey
- Princeton, New Jersey
- Stratford, New Jersey
- Toms River, New Jersey
- Albuquerque, New Mexico
- Albuquerque, New Mexico
- Albany, New York
- Albany, New York
- Albany, New York
- Brooklyn, New York
- Cedarhurst, New York
- Elmsford, New York
- Latham, New York
- Liverpool, New York
- New Hyde Park, New York
- New York, New York
- New York, New York
- New York, New York
- New York, New York
- Orangeburg, New York
- Rochester, New York
- Durham, North Carolina
- Hickory, North Carolina
- Hickory, North Carolina
- Raleigh, North Carolina
- Winston-Salem, North Carolina
- Beachwood, Ohio
- Canton, Ohio
- Canton, Ohio
- Cleveland, Ohio
- Columbus, Ohio
- Dayton, Ohio
- Toledo, Ohio
- Oklahoma City, Oklahoma
- Oklahoma City, Oklahoma
- Medford, Oregon
- Portland, Oregon
- Portland, Oregon
- Portland, Oregon
- Abington, Pennsylvania
- Allentown, Pennsylvania
- Jenkintown, Pennsylvania
- Philadelphia, Pennsylvania
- Philadelphia, Pennsylvania
- Philadelphia, Pennsylvania
- Pittsburgh, Pennsylvania
- Pittsburg, Pennsylvania
- East Providence, Rhode Island
- Providence, Rhode Island
- Providence, Rhode Island
- N. Charleston, South Carolina
- Sioux Falls, South Dakota
- Cordova, Tennessee
- Franklin, Tennessee
- Johnson City, Tennessee
- Knoxville, Tennessee
- Austin, Texas
- Dallas, Texas
- Dallas, Texas
- DeSoto, Texas
- Fort Worth, Texas
- Houston, Texas
- Houston, Texas
- San Antonio, Texas
- San Antonio, Texas
- Wichita Falls, Texas
- Salt Lake City, Utah
- Salt Lake City, Utah
- Bennington, Vermont
- Burlington, Vermont
- Alexandria, Virginia
- Charlottesville, Virginia
- Richmond, Virginia
- Seattle, Washington
- Seattle, Washington
- Wenatchee, Washington
- Madison, Wisconsin
- Milwaukee, Wisconsin
- Waukesha, Wisconsin
- Graz, Styria
- Wien, Vienna
- Calgary, Alberta
- Kamloops, British Columbia
- Kelowna, British Columbia
- Penticton, British Columbia
- Vancouver, British Columbia
- Kingston, Ontario
- London, Ontario
- London, Ontario
- Ottawa, Ontario
- Peterborough, Ontario
- Toronto, Ontario
- Toronto, Ontario
- Whitby, Ontario
- Greenfield Park, Quebec
- Montreal, Quebec
- Montréal, Quebec
- Sherbrooke, Quebec
- Verdun, Quebec
- Tübingen, Baden-wuerttemberg
- Ulm, Baden-wuerttemberg
- Freiburg, Baden-Württemberg
- Günzburg, Bayern
- München, Bayern
- München, Bayern
- Regensburg, Byern
- Bochum, Nordrhein-westfalen
- Homburg/Saar, Saarland
- Leipzig, Sachen
- Dresden, Saschen
- Hamburg,
- Birmingham, Alabama
- Goodyear, Arizona
- Phoenix, Arizona
- Phoenix, Arizona
- Sun City, Arizona
- Tucson, Arizona
- Tucson, Arizona
- Little Rock, Arkansas
- Berkeley, California
- Carson, California
- Costa Mesa, California
- Encino, California
- Fresno, California
- Fullerton, California
- La Jolla, California
- La Jolla, California
- Laguna Hills, California
- Long Beach, California
- Los Alamitos, California
- Los Angeles, California
- Newport Beach, California
- Oceanside, California
- Orange, California
- Pasadena, California
- Sacramento, California
- Sacramento, California
- San Diego, California
- San Diego, California
- San Francisco, California
- San Francisco, California
- Santa Monica, California
- Sherman Oaks, California
- Walnut Creek, California
- Boulder, Colorado
- Denver, Colorado
- Fort Collins, Colorado
- Danbury, Connecticut
- Fairfield, Connecticut
- New Haven, Connecticut
- New Haven, Connecticut
- Norwalk, Connecticut
- Waterbury, Connecticut
- Newark, Delaware
- Washington, District of Columbia
- Atlantis, Florida
- Bradenton, Florida
- Deerfield Beach, Florida
- Delray Beach, Florida
- Fort Lauderdale, Florida
- Fort Myers, Florida
- Fort Myers, Florida
- Fort Walton Beach, Florida
- Hallandale Beach, Florida
- Jacksonville, Florida
- Maitland, Florida
- Melbourne, Florida
- Miami, Florida
- Miami, Florida
- Miami, Florida
- Miami, Florida
- Ocala, Florida
- Orlando, Florida
- Palm Beach Gardens, Florida
- Port Charlotte, Florida
- Saint Petersburg, Florida
- Sarasota, Florida
- Tampa, Florida
- Tampa, Florida
- Tampa, Florida
- Tampa, Florida
- West Palm Beach, Florida
- Atlanta, Georgia
- Atlanta, Georgia
- Atlanta, Georgia
- Columbus, Georgia
- Columbus, Georgia
- Decatur, Georgia
- Lawrenceville, Georgia
- Chicago, Illinois
- Elk Grove Village, Illinois
- Peoria, Illinois
- Springfield, Illinois
- Elkhart, Indiana
- Indianapolis, Indiana
- Kansas City, Kansas
- Lenexa, Kansas
- Lexington, Kentucky
- Lexington, Kentucky
- Paducah, Kentucky
- Lake Charles, Louisiana
- Shreveport, Louisiana
- Scarborough, Maine
- Rockville, Maryland
- Boston, Massachusetts
- Boston, Massachusetts
- Haverhill, Massachusetts
- Newton, Massachusetts
- Pittsfield, Massachusetts
- Plymouth, Massachusetts
- Springfield, Massachusetts
- Ann Arbor, Michigan
- Detroit, Michigan
- East Lansing, Michigan
- Kalamazoo, Michigan
- Rochester, Minnesota
- Hattiesburg, Mississippi
- Kansas City, Missouri
- Saint Louis, Missouri
- Saint Lous, Missouri
- Billings, Montana
- Great Falls, Montana
- Omaha, Nebraska
- Eatontown, New Jersey
- Manchester, New Jersey
- Princeton, New Jersey
- Toms River, New Jersey
- Albuquerque, New Mexico
- Albany, New York
- Albany, New York
- Albany, New York
- Elmsford, New York
- Latham, New York
- Liverpool, New York
- New Hyde Park, New York
- New York, New York
- New York, New York
- Orangeburg, New York
- Rochester, New York
- Durham, North Carolina
- Hickory, North Carolina
- Raleigh, North Carolina
- Canton, Ohio
- Columbus, Ohio
- Dayton, Ohio
- Oklahoma City, Oklahoma
- Oklahoma City, Oklahoma
- Medford, Oregon
- Portland, Oregon
- Portland, Oregon
- Portland, Oregon
- Abington, Pennsylvania
- Allentown, Pennsylvania
- Jenkintown, Pennsylvania
- Philadelphia, Pennsylvania
- Philadelphia, Pennsylvania
- Philadelphia, Pennsylvania
- Pittsburgh, Pennsylvania
- Pittsburgh, Pennsylvania
- East Providence, Rhode Island
- Providence, Rhode Island
- Providence, Rhode Island
- North Charleston, South Carolina
- Sioux Falls, South Dakota
- Cordova, Tennessee
- Johnson City, Tennessee
- Knoxville, Tennessee
- Nashville, Tennessee
- Austin, Texas
- Dallas, Texas
- Dallas, Texas
- DeSoto, Texas
- Fort Worth, Texas
- Houston, Texas
- San Antonio, Texas
- San Antonio, Texas
- Salt Lake City, Utah
- Salt Lake City, Utah
- Bennington, Vermont
- Burlington, Vermont
- Alexandria, Virginia
- Charlottesville, Virginia
- Richmond, Virginia
- Seattle, Washington
- Seattle, Washington
- Milwaukee, Wisconsin
- Waukesha, Wisconsin
- Graz, Styria
- Calgary, Alberta
- Kamloops, British Columbia
- Kelowna, British Columbia
- Kingston, Ontario
- London, Ontario
- Ottawa, Ontario
- Toronto, Ontario
- Toronto, Ontario
- Whitby, Ontario
- Greenfield Park, Quebec
- Montréal, Quebec
- Montréal, Quebec
- Sherbrooke, Quebec
- Verdun, Quebec
- Providence, Rhode Island
- Sun City, Arizona
- Irvine, California
- Los Alamitos, California
- Northridge, California
- San Diego, California
- San Francisco, California
- New Haven, Connecticut
- Washington, District of Columbia
- Delray Beach, Florida
- Jacksonville, Florida
- Chicago, Illinois
- Indianapolis, Indiana
- Boston, Massachusetts
- Ann Arbor, Michigan
- Rochester, Minnesota
- Long Branch, New Jersey
- New York City, New York
- Rochester, New York
- Durham, North Carolina
- Portland, Oregon
- Pittsburgh, Pennsylvania
- Providence, Rhode Island
- Dallas, Texas
- Houston, Texas
- Bennington, Vermont
- Seattle, Washington
Descriptive Information | ||||
---|---|---|---|---|
Brief Title ICMJE | Study Evaluating SRA-333 in Mild to Moderate Alzheimer's Disease (AD) | |||
Official Title ICMJE | A Randomized, Double-blind, Placebo-controlled, Safety, Tolerability, Pharmacokinetics, Pharmacodynamics Trial of Multiple Ascending Fixed Doses of SRA-333 in Subjects With Mild to Moderate Alzheimer's Disease. | |||
Brief Summary | To determine the safety and tolerability of multiple ascending fixed oral doses of SRA-333 in subjects with mild to moderate Alzheimer's disease. | |||
Detailed Description | Not Provided | |||
Study Type ICMJE | Interventional | |||
Study Phase ICMJE | Phase 2 | |||
Study Design ICMJE | Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double Primary Purpose: Treatment | |||
Condition ICMJE | Alzheimer's Disease | |||
Intervention ICMJE | Drug: SRA-333 | |||
Study Arms ICMJE | Not Provided | |||
Publications * | Not Provided | |||
* Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline. | ||||
Recruitment Information | ||||
Recruitment Status ICMJE | Completed | |||
Enrollment ICMJE | 16 | |||
Original Enrollment ICMJE | Same as current | |||
Actual Study Completion Date ICMJE | April 2005 | |||
Actual Primary Completion Date | April 2005 (Final data collection date for primary outcome measure) | |||
Eligibility Criteria ICMJE | Inclusion Criteria:
Exclusion Criteria:
Other exclusions apply | |||
Sex/Gender ICMJE |
| |||
Ages ICMJE | 50 Years to 85 Years (Adult, Older Adult) | |||
Accepts Healthy Volunteers ICMJE | No | |||
Contacts ICMJE | Contact information is only displayed when the study is recruiting subjects | |||
Listed Location Countries ICMJE | United States | |||
Removed Location Countries | ||||
Administrative Information | ||||
NCT Number ICMJE | NCT00151333 | |||
Other Study ID Numbers ICMJE | 3098A1-200 | |||
Has Data Monitoring Committee | Not Provided | |||
U.S. FDA-regulated Product | Not Provided | |||
IPD Sharing Statement ICMJE | Not Provided | |||
Responsible Party | Not Provided | |||
Study Sponsor ICMJE | Wyeth is now a wholly owned subsidiary of Pfizer | |||
Collaborators ICMJE | Not Provided | |||
Investigators ICMJE |
| |||
PRS Account | Wyeth is now a wholly owned subsidiary of Pfizer | |||
Verification Date | September 2009 | |||
ICMJE Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP |