Eligibility criteria
Condition
Premenstrual Syndrome
Sex
Female
Age
18-49 years
Inclusion criteria
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- Healthy women aged 18 to 49 years
- Regular 21 to 35 day menstrual cycles for 3 months prior to study visit 1
- History of menstrual cycle related symptoms as determined by the investigator.
Exclusion criteria
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- Contraindication to combination oral contraceptives
- Depression requiring hospitalization or associated with suicidal ideation within the
last 3 years
- Use of antidepressants/anxiolytics within 10 days of screening and for the duration of
the study.