Prospective Registry of European Hemophilia B Patients Receiving BeneFIX® for Usual Use

This is an open-label multi-center Registry in patients with hemophilia B receiving BeneFIX.
All patients who begin treatment with BeneFIX in European Union countries, will be eligible
for participation. Patient demographics will be collected at baseline for all patients. A
baseline FIX activity and Bethesda assay for inhibitor based on historical data should be
recorded if available. Adverse events as defined in the protocol will also be reported on the
appropriate forms. Data will be collected from patients on an ongoing basis to ensure that
information is being captured for each patient being treated with BeneFIX.