- All patients admitted to or transferred to the MICU.
- Patients 18 years of age or older.
- Provide written informed consent.
- Patients known to be infected or colonized by VRE or ESBL-producing E.coli,
- Patients who have hypersensitivity to penicillin.
- Any underlying conditions or diseases that will be ultimately fatal within 48 hours.
- Any concurrent condition or medication which would interfere with absorption or
metabolism of study drugs.