- Meet DSM IV criteria for Panic Disorder (with or without agoraphobia) for at least 3
months before study day 1.
- Have a minimum of 8 full-symptom panic attacks during the 4 weeks before the screening
- Provide a written informed consent
- Treatment with Venlafaxine within 6 months of study day 1, as well Paroxetine
- Known hypersensitivity to Venlafaxine or related compounds as well to Paroxetine.
- Psychopharmacologic drugs within 14 days of study day 1