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A Trial To Evaluate Two Antibiotics For The Treatment Of Acute Exacerbation Of Chronic Bronchitis (AECB)

Last updated on March 15, 2019

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Study Location
Pfizer Investigational Site
Guangzhou, Guangdong, 510080 China
Contact
1-800-718-1021
Eligibility criteria
Condition
The disease, disorder, syndrome, illness, or injury that is being studied.
Chronic Bronchitis
Sex
Females and Males
Age
Pediatric Trials: 0-17 Years
Adult Trials: 18+ Years
50 + years
Inclusion criteria
The factors, or reasons, that allow a person to participate in a clinical study.
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- Diagnosis of chronic bronchitis (chronic cough and sputum production on most days for
three consecutive months for more than two consecutive years) and clinical evidence of
AECB as demonstrated by both the following symptoms:

- Production of purulent sputum as defined by Gram stained sputum specimen

- Presence of all of the following:

- Increased sputum production

- Increased dyspnea

- Increased cough

- At least two exacerbations of AECB in the past 12 months

- Documented FEV1 less than 80% of predicted

Exclusion criteria
The factors, or reasons, that prevent a person from participating in a clinical study.
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- A chest radiograph consistent with pneumonia

- Treatment with any systemic antibiotic within the twenty-one days prior to study entry
or those with a chance of receiving other systemic antibiotics during study
participation

NCT00254566
Pfizer
Completed
A Trial To Evaluate Two Antibiotics For The Treatment Of Acute Exacerbation Of Chronic Bronchitis (AECB)

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