Eligibility criteria
Condition
Graft Rejection, Kidney Failure, Kidney Transplantation
Sex
Females and Males
Age
18-65 years
Inclusion criteria
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- Age: 18 and
- End-stage renal disease, with patients scheduled to receive a primary renal allograft
from a cadaveric donor
- Patients receiving a second transplant without an immunological loss of their first
graft in the first six months of transplant
Exclusion criteria
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- Evidence of active systemic or localized major infection at the time of initial
sirolimus administration
- Evidence of infiltrate, cavitation, or consolidation on chest x-ray obtained during
pre-study screening
- Use of any investigational drug or treatment up to 4 weeks prior to enrollment to the
study and during the 12-month treatment phase