This is an observational prospective, multicenter study. The aim of the study is to evaluate
how the Italian population of patients are treated with early aggressive RA, defined by the
Italian Society of Rheumatology Guidelines, (GIARA Registry Study Group. Clin Exp Rheumatol
2003;21(Suppl. 31):S129-S132), in rheumatologic clinical practice and whether recent
scientific evidence or new treatments available to rheumatologists can change their practice
in a 2 year follow-up. The observation will primarily focus on the disease activity and
clinical remission in patients who are receiving different treatment strategies. The primary
goal is to define prevalence of clinical remission, according to the (Disease Activity Score)
DAS 28 definition of clinical remission, in patients with early aggressive RA receiving
different therapies at 1 year.
Secondary objective are assessment of:
- Prevalence of Remission at the second year
- Disease activity at the first and second year.
- ACR 20%, 50%, 70% response at the first and second year.
- Quality of Life in patients with or without remission at the first and second year
- Safety Evaluations