- Subjects seeking medical treatment for symptoms consistent with IC that have been
ongoing for > 9 months or seeking medical treatment for a previous documented
diagnosis of IC
- Subjects who are not surgically sterile or postmenopausal (amenorrheic > 12 months)
must agree and commit to the use of a medically acceptable, highly–effective (i.e.
double-barrier or IUD), non-hormonal form of birth control during the study and for 30
days after the last dose of test
- Use of herbal supplements (except for a daily multivitamin/mineral supplement not
containing herbal components)
- History of cancer (other than resected cutaneous basal or squamous cell carcinoma or
in situ cervical cancer) with less than 5 years documentation of a disease-free state
- Vaginitis or vaginal infection within 1 month before randomization