- Participants must have stable, documented cardiovascular disease (including at least
one of the following diagnosed > 2 months prior to the Screening visit - angina,
myocardial infarction (MI), revascularization, transient ischemic attack (TIA), and
peripheral vascular disease (PVD).
- Participants that smoke > 10 cigarettes / day.
- Participants with unstable cardiovascular disease
- Cardiovascular events in the past 2 months
- Moderate or severe chronic obstructive pulmonary disease (COPD)