ABOUT THIS STUDY
Patients with a systemic right ventricle and a subpulmonic left ventricle-including patients with transposition of the great arteries (d-TGA) who have undergone Mustard and Senning repairs (atrial switch procedures) and patients with congenitally corrected TGA (l-TGA) Subpulmonic right ventricle in the absence of pulmonary hypertension (repaired tetralogy of Fallot, congenital pulmonic regurgitation) 4-chambered heart Age > 18 years Participants will have either acquired left ventricular dysfunction (ejection fraction < 35%) or no known cardiac disease For the control group, individuals will have normal cardiac anatomy and normal left ventricular function (determined by echocardiogram) and no known cardiac disease.
Single ventricle and or single atria Liver disease with portal hypertension Renal disease
requiring dialysis Creatine > 4.0 Significant pulmonary hypertension (systolic PAP >60 mmHg
by Echo) Uncontrolled systemic arterial hypertension (systolic > 200 mmHg or diastolic >105
mmHg) Myocardial infarction or acute coronary syndrome within 2 months D-TGA status post
atrial switch procedure (Jatene) Intracardiac shunts Inadequate echocardiogram windows
Coronary Angioplasty 30 days
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