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CARDS Is Designed To Show If Lowering Cholesterol With Atorvastatin In Type 2 Diabetics Without CV Disease Reduces The Risk Of CV Events

Last updated on March 14, 2019

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Study Location
Pfizer Investigational Site
Fosterhill, Aberdeen, AB25 2XG United Kingdom
Contact
1-800-718-1021
Eligibility criteria
Condition
The disease, disorder, syndrome, illness, or injury that is being studied.
Major Coronary Event, Cerebrovascular Accident, Coronary Artery Bypass Graft, Unstable Angina, Revascularization
Sex
Females and Males
Age
Pediatric Trials: 0-17 Years
Adult Trials: 18+ Years
40-75 years
Inclusion criteria
The factors, or reasons, that allow a person to participate in a clinical study.
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Patients must have a documented history of at least one of the following:

- Hypertension (defined as systolic blood pressure 140 mmHg or a diastolic blood
pressure 90 mmHg (defined as the disapperance of all sound [Korotkoff Phase V] or
receiving anti-hypertensive treatment. Blood pressure should be measured after sitting
the patient quietly for 3 minutes).

- Retinopathy (defined as any of the following; non-proliferative retinopathy,
pre-pre-proliferative retinopathy, proliferative retinopathy, maculopathy, advanced
diabetic eye disease or history of photocoagulation).

- Microalbuminuria (defined as either, Albumin creatinine ratio > than = to 2.5 mg/mmol,
or Albumin excretion rate on a timed collection > than = to 20 mcg/min (> than = to 30
mg/24hrs) on two successive occasions, or a positive micral or other strip test).

- Macroalbuminuria (defined as either; Albustix or other dipstick evidence of gross
proteinuria, Albumin creatinine ratio > than = to 25 mg/mmol; or Albumin excretion
rate on a timed collection > than = 200 mcg/min (> than = 300 mg/24hrs) on two
sucessive occasions).

- Current smoker

Exclusion criteria
The factors, or reasons, that prevent a person from participating in a clinical study.
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- Type I Diabetes Mellitus

- Any major Coronary event prior to entry into the study

NCT00327418
Pfizer
Completed
CARDS Is Designed To Show If Lowering Cholesterol With Atorvastatin In Type 2 Diabetics Without CV Disease Reduces The Risk Of CV Events

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