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An Open Label Trial to Investigate Macugen for the Preservation of Visual Function in Subjects With Neovascular AMD

Last updated on February 23, 2019

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Study Location
Pfizer Investigational Site
Graz, , A-8036 Austria
Contact
1-800-718-1021
Eligibility criteria
Condition
The disease, disorder, syndrome, illness, or injury that is being studied.
Age Related Macular Degeneration (AMD), Macular Degeneration, Choroidal Neovascularization (CNV)
Sex
Females and Males
Age
Pediatric Trials: 0-17 Years
Adult Trials: 18+ Years
50 + years
Inclusion criteria
The factors, or reasons, that allow a person to participate in a clinical study.
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- Evidence of neovascular AMD in at least one eye. In subjects with bilateral
neovascular AMD, only one eye would be eligible for enrollment

- Baseline visual acuity of greater than or equal to 20/320, or better than 25 ETDRS
letters in the study eye

Exclusion criteria
The factors, or reasons, that prevent a person from participating in a clinical study.
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- Previous treatment for CNV secondary to AMD, including any prior PDT with verteporfin,
thermal laser photocoagulation, external beam radiation or transpupillary
thermotherapy to the study eye

- Subjects having subfoveal fibrosis/ scar or atrophy representing > 25% of the total
lesion size

NCT00327470
Pfizer
Terminated
An Open Label Trial to Investigate Macugen for the Preservation of Visual Function in Subjects With Neovascular AMD

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[email protected]

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