- The patient's ASA physical status is 1 or 2 and he has a low risk (i.e., developing an acute coronary event within the next 10 years according to the PROCAM
risk assessment calculator.
- The patient is scheduled to undergo routine radical prostatectomy performed under a
standardized regimen of general anesthesia, and is expected to experience moderate to
severe postsurgical pain in the absence of postoperative analgesia.
- The patient has a history of uncontrolled chronic disease or a concurrent clinically
significant illness or medical condition such as a diagnosed chronic pain condition,
which, in the Investigator's opinion, would contraindicate study participation or
confound interpretation of the results
- The patient has a history or current presence of congestive heart failure (NYHA
II-IV), established ischaemic heart disease, peripheral arterial disease and / or