- Females and males 18 years of age and older with uncomplicated, symptomatic malaria as
as indicated by the presence of both of the following:
- Blood smears positive for Plasmodium falciparum asexual parasitemia between 1000
- Documented fever (38.5 C/101.3 F rectal or tympanic; 37.5 C/99.5 F axillary or 38
C/100.4 F oral) or history of fever (as reported by subject) within the prior 24
- Severe or complicated malaria.
- Pregnant or breast-feeding women.