Safety, Toleration and Efficacy of CP-741,952 for the Treatment of Obesity


Last updated date
Study Location
Pfizer Investigational Site
Ann Arbor, Michigan, 48105, United States


Contact a representative by phone, email, or visiting the study website. Please see the references below:

By phone

Pfizer Clinical Trials Contact Center


By email


[email protected]

Call Now

Eligibility Criteria
The disease, disorder, syndrome, illness, or injury that is being studied.
Females and Males
Pediatric Trials: 0-17 Years
Adult Trials: 18+ Years
18-65 years
Inclusion Criteria
The factors, or reasons, that allow a person to participate in a clinical study.
Show details

- BMI of 30-40 kg/m2

Exclusion Criteria
The factors, or reasons, that prevent a person from participating in a clinical study.
Show details

- Women of childbearing potential


Questions about a trial? Call or email to reach a Pfizer Clinical Trial Contact Center Representative

Pfizer Clinical Trials Contact Center


[email protected]

pfizer-logoClinical Trials
Interested in learning more about clinical trials?
Discover how clinical trials work and the impact your participation could have.


Search for Clinical Trials by condition, keyword or trial number. Share your location or enter your city or zip code to find studies near you.

Based on your search, you may also be interested in

ObesityA 26-Week, 2-Part Study to Evaluate the Efficacy and Safety of PF-06882961 in Adults With Obesity
  1. Winnipeg, Manitoba
  2. Quebec,
  3. Anniston, Alabama
  4. Anaheim, California
  5. Los Angeles, California
  6. Orlando, Florida
  7. Gurnee, Illinois
  8. Evansville, Indiana
  9. Valparaiso, Indiana
  10. Topeka, Kansas
  11. Louisville, Kentucky
  12. Omaha, Nebraska
  13. Omaha, Nebraska
  14. Hickory, North Carolina
  15. Raleigh, North Carolina
  16. Salisbury, North Carolina
  17. Wilmington, North Carolina
  18. Fargo, North Dakota
  19. Cleveland, Ohio
  20. Moncks Corner, South Carolina
  21. North Charleston, South Carolina
  22. Summerville, South Carolina
  23. Summerville, South Carolina
  24. Bristol, Tennessee
  25. Bristol, Tennessee
  26. Bristol, Tennessee
  27. Knoxville, Tennessee
  28. Brampton, Ontario
  29. London, Ontario
  30. Toronto, Ontario
  31. Chicoutimi, Quebec
  32. Sherbrooke, Quebec
  33. Quebec,
  34. Suita-shi, Osaka
  35. Chuo-ku, Tokyo
  36. Chuo-ku, Tokyo
  37. Shinjuku-ku, Tokyo
18 Years+
ObesityPharmacokinetics Of Tigecycline In Morbidly Obese Subjects
  1. Albany, New York
18 Years+
Advanced Information
Descriptive Information
Brief Title  ICMJE Safety, Toleration and Efficacy of CP-741,952 for the Treatment of Obesity
Official Title  ICMJE A 12-Week, Phase 2A, Randomized, Subject And Investigator Blind, Placebo-Controlled Trial To Evaluate The Effect Of CP-741,952 On Weight Loss In Otherwise Healthy Overweight And Obese Adult Subjects
Brief Summary The purpose of this study is to determine whether CP-741,952 is effective in the treatment of obesity and to determine 12 week safety and toleration.
Detailed Description Following review of the preliminary data from completed study A7081004, the development program for CP-741,952 was terminated on 15 March 2007. Primary reasons for program termination included a lack of significant efficacy at all doses investigated and an increased incidence of mild to moderate elevations in serum transaminases, primarily alanine aminotransferase (ALT), and liver fat content, in treated compared to placebo subjects. A synopsis will be created and will include greater detail on these findings.
Study Type  ICMJE Interventional
Study Phase  ICMJE Phase 2
Study Design  ICMJE Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single
Primary Purpose: Treatment
Condition  ICMJE Obesity
Intervention  ICMJE Drug: CP-741,952
Study Arms  ICMJE Not Provided
Publications * Not Provided

*   Includes publications given by the data provider as well as publications identified by Identifier (NCT Number) in Medline.
Recruitment Information
Recruitment Status  ICMJE Terminated
Enrollment  ICMJE
 (submitted: August 21, 2006)
Original Enrollment  ICMJE Same as current
Actual Study Completion Date  ICMJE April 2007
Primary Completion Date Not Provided
Eligibility Criteria  ICMJE

Inclusion Criteria:

  • BMI of 30-40 kg/m2

Exclusion Criteria:

  • Women of childbearing potential
Sex/Gender  ICMJE
Sexes Eligible for Study:All
Ages  ICMJE 18 Years to 65 Years   (Adult, Older Adult)
Accepts Healthy Volunteers  ICMJE Yes
Contacts  ICMJE Contact information is only displayed when the study is recruiting subjects
Listed Location Countries  ICMJE United States
Removed Location Countries  
Administrative Information
NCT Number  ICMJE NCT00367783
Other Study ID Numbers  ICMJE A7081004
Has Data Monitoring Committee No
U.S. FDA-regulated Product Not Provided
IPD Sharing Statement  ICMJE Not Provided
Responsible Party Not Provided
Study Sponsor  ICMJE Pfizer
Collaborators  ICMJE Not Provided
Investigators  ICMJE
Study Director:Pfizer Call CenterPfizer
PRS Account Pfizer
Verification Date July 2011

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP