- Patient must have a malignant, solid tumor that has been diagnosed as having
metastasized to bone, and must have moderate to severe pain secondary to the bone
metastasis at an identifiable reference site.
- The patient who has undergone diagnostic or therapeutic invasive interventions
(angiography, biopsy, surgery) less than 15 days prior to study start that would
impact their assessment of pain at the reference pain site or area, in the opinion of