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Combination of Irinotecan and Temozolomide in Children With Brain Tumors.

Last updated on March 15, 2019

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Study Location
Pfizer Investigational Site
Westmead, New South Wales, 2145 Australia
Contact
1-800-718-1021
Eligibility criteria
Condition
The disease, disorder, syndrome, illness, or injury that is being studied.
Glioma, Medulloblastoma
Sex
Females and Males
Age
Pediatric Trials: 0-17 Years
Adult Trials: 18+ Years
6-18 months
Inclusion criteria
The factors, or reasons, that allow a person to participate in a clinical study.
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- Cohort 1: Recurrent or refractory medulloblastoma in which current standard treatment
approaches have failed; biopsy is not required for recurrent disease.

- Cohort 2: Newly-diagnosed high-grade glioma (World Health Organization [WHO] grade 3
or 4)

- Life expectancy ≥ 3 months

Exclusion criteria
The factors, or reasons, that prevent a person from participating in a clinical study.
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- Diagnosis of brainstem glioma

- Concurrent administration of any other anti-tumor therapy

- Pre-existing uncontrolled diarrhea

NCT00404495
Pfizer
Completed
Combination of Irinotecan and Temozolomide in Children With Brain Tumors.

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Pfizer Clinical Trials Contact Center

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[email protected]

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Contact a representative by phone, email, or visiting the study website. Please see the references below:

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Pfizer Clinical Trials Contact Center

1-800-718-1021

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[email protected]

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