- Histologically documented MCL.
- Must have received at least one prior therapy.
- Eastern Cooperative Oncology Group (ECOG) performance status ≤1.
- Adequate organ function as outlined in the protocol.
- Major surgery, radiation therapy, or systemic therapy within 4 weeks of study
- Prior radiation therapy to >25% of the bone marrow (whole pelvis is 25%).
- Uncontrolled brain metastases, spinal cord compression, carcinomatous meningitis, or