Eligibility criteria
Condition
Ankylosing Spondylitis
Sex
Females and Males
Age
18-70 years
Inclusion criteria
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- Active and severe ankylosing spondylitis
- Ankylosing spondylitis refractory to standard anti-rheumatic treatment
- Between 18 and 70 years of age
Exclusion criteria
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- Prior exposure to any TNF-inhibitor, including etanercept
- DMARDs (other than hydroxychloroquine, methotrexate and sulphasalazine) within 4 weeks
of study drug initiation
- Dose of NSAIDs changed within two weeks of study drug initiation