Eligibility criteria
Condition
Rheumatoid Arthritis
Sex
Females and Males
Age
18-75 years
Inclusion criteria
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- Men or women of nonchildbearing potential with rheumatoid arthritis (RA), aged 18 to
75 years
- RA disease onset after 16 years of age and has had the disease for at least 6 months
- Must be receiving a stable, well-tolerated oral dose of methotrexate (5 to 25 mg)
taken once weekly for at least 3 months
Exclusion criteria
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- Evidence of unstable clinically significant disease