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Study Evaluating the Potential of DVS SR to Inhibit the CYP2D6 Pathway

Last updated on February 20, 2019

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Study Location
Contact
1-800-718-1021
Eligibility criteria
Condition
The disease, disorder, syndrome, illness, or injury that is being studied.
Major Depressive Disorder, Diabetic Neuropathies, Fibromyalgia, Vasomotor Symptoms
Sex
Male
Age
Pediatric Trials: 0-17 Years
Adult Trials: 18+ Years
18-45 years
Inclusion criteria
The factors, or reasons, that allow a person to participate in a clinical study.
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- Healthy men and nonlactating and nonpregnant women of nonchildbearing potential aged
from 18 to 45 years.

- Body mass index in the range of 18 to 30 kg/m2 and body weight ≥50 kg.

- Nonsmoker or smoker of fewer than 10 cigarettes per day as determined by history.

Exclusion criteria
The factors, or reasons, that prevent a person from participating in a clinical study.
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- History of bronchial asthma, of seizure disorder (other than a single childhood
febrile seizure)and of any clinically important drug allergy and any known allergy to
desvenlafaxine, venlafaxine, paroxetine, codeine, or any of the non-active excipients
in the dosage forms.

- Use of any CYP2D6 inhibitors or inducers within 30 days before test article
administration.

- Demonstration of a positive orthostatic test at screening.

NCT00456898
Pfizer
Completed
Study Evaluating the Potential of DVS SR to Inhibit the CYP2D6 Pathway

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Pfizer Clinical Trials Contact Center

1-800-718-1021

[email protected]

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FOR MORE INFORMATION

Contact a representative by phone, email, or visiting the study website. Please see the references below:

BY PHONE

Pfizer Clinical Trials Contact Center

1-800-718-1021

BY EMAIL

Contact

[email protected]

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