Eligibility criteria
Condition
Pancreatic Ductal Carcinoma
Sex
Females and Males
Age
18 + years
Inclusion criteria
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- Histologically or cytologically confirmed, metastatic or locally-, advanced pancreatic
adenocarcinoma not amenable to curative resection.
- Adequate renal, hepatic and bone marrow function.
- Performance status 0 or 1.
Exclusion criteria
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- Prior treatment with any systemic chemotherapy for metastatic disease.
- Prior treatment with gemcitabine, AG-013736, or other vascular endothelial growth
factor inhibitors.
- Current or recent bleeding, thromboembolic event and or use of a thrombolytic agent.
- Inability to take oral medication.