Eligibility criteria
Condition
Postmenopause
Sex
Female
Age
35-70 years
Inclusion criteria
Show details
- Healthy, postmenopausal women, aged 35 to 70 years
- Spontaneous amenorrhea for at least 12 months (no FSH required) or spontaneous
amenorrhea for at least 6 months (FSH level ≥38 mIU/mL); spontaneous amenorrhea must
have begun by the age of 55
- BMI in the range of 18 to 35 kg/m2
Exclusion criteria
Show details
- History or presence of hypertension (>139 mm Hg systolic or >89 mm Hg diastolic)
- History of drug allergy to conjugated estrogens (CE) or selective estrogen receptor
modulators (SERMs)
- Use of prescription or investigatioanl drugs within 30 days before test article
administration