- Normal body mass index and weight
- No significant diseases in the medical history or clinically significant findings on
physical exam, opthalmologic exam, clinical laboratory evaluations or 12-lead
electrocardiogram
- Current illness or history of medical condition affecting the body's function
- Use of any medication within 7 days, any immunosuppressive medication within 6 months,
any investigational drug within 30 days or any vaccine or immunoglobulin within 90
days
- Use of any medications during the study
- Positive TB test
- Smoking within 6 months
- Pregnancy or risk of Pregnancy
- Alcohol or drug misuse within 60 days
- Sensitivity to quinazolines