- Postmenopausal women aged 35 to 70 years.
- Spontaneous or surgical amenorrhea for at least 6 months.
- Body mass index (BMI) in the range of 18.0 to 35.0 kg/m2 and body weight greater than
or equal to 50 kg.
- Hypertension or elevated supine blood pressure (>139 mm Hg systolic or >89 mm Hg
- History of any clinically important drug allergy.
- Use of any prescription or investigational drug within 30 days before test article