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A Study Of PF-03732010 In Patients With Advanced Solid Tumors

Last updated on February 20, 2019

FOR MORE INFORMATION
Study Location
Pfizer Investigational Site
Philadelphia, Pennsylvania, 19111 United States
Contact
1-800-718-1021
Eligibility criteria
Condition
The disease, disorder, syndrome, illness, or injury that is being studied.
Neoplasms
Sex
Females and Males
Age
Pediatric Trials: 0-17 Years
Adult Trials: 18+ Years
18 + years
Inclusion criteria
The factors, or reasons, that allow a person to participate in a clinical study.
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- Advanced solid tumors refractory to (or intolerant of) established therapy known to
provide clinical benefit, or for which there is no standard therapy

- Age >= 18 years of age

- Adequate bone marrow function as defined by: absolute neutrophil count (ANC) ≥1500/uL,
hemoglobin ≥ 9 g/dL, platelets > 100,000/uL

- Adequate liver function as defined by: bilirubin ULN, or

- Serum creatinine

- ECOG status 0-1

- Availability of biopsy tumor tissue (or fine needle aspirate) for testing of
P-cadherin expression

- Tumor tissue (or fine needle aspirate) showing over-expression of P-cadherin

- Must be able to give written informed consent

- Be able to comply with scheduled study visits, treatment plans, laboratory tests and
other procedures

Exclusion criteria
The factors, or reasons, that prevent a person from participating in a clinical study.
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- Chemotherapy, radiotherapy, or any investigational cancer therapy within 4 weeks of
study entry

- Patients with carcinomatous meningitis or untreated brain metastases.

- History of significant low platelet count, and/or bleeding disorders, requiring
medical or surgical intervention

- History of significant bleeding episodes within 6 months, unless the source of
bleeding has been resected

NCT00557505
Pfizer
Completed
A Study Of PF-03732010 In Patients With Advanced Solid Tumors

NEED INFO?

Questions about a trial? Call or email to reach a Pfizer Clinical Trial Contact Center

Pfizer Clinical Trials Contact Center

1-800-718-1021

[email protected]

call now

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FOR MORE INFORMATION

Contact a representative by phone, email, or visiting the study website. Please see the references below:

BY PHONE

Pfizer Clinical Trials Contact Center

1-800-718-1021

BY EMAIL

Contact

[email protected]

Call Now