- Men aged 18 to 45 years inclusive on study day 1.
- Elderly men and women aged 65 to 80 years inclusive on study day 1.
- Women must be postmenopausal for > or = 1 year (with estradiol
40 mIU/mL).
- Healthy as determined by the investigator on the basis of medical history, physical
examination, vital signs, clinical laboratory test results, and 12-leave
electrocardiogram.
- Elderly subjects may have stable, nonclinically significant abnormalities on physical
examination, and laboratory evaluation.
- Non-smoker.
- Men aged 18 to 45 years inclusive on study day 1.
- Elderly men and women aged 65 to 80 years inclusive on study day 1.
- Women must be postmenopausal for > or = 1 year (with estradiol
40 mIU/mL).
- Healthy as determined by the investigator on the basis of medical history, physical
examination, vital signs, clinical laboratory test results, and 12-leave
electrocardiogram.
- Elderly subjects may have stable, nonclinically significant abnormalities on physical
examination, and laboratory evaluation.
- Non-smoker.