Eligibility criteria
Condition
Colorectal Neoplasms
Sex
Females and Males
Age
18 + years
Inclusion criteria
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- Adenocarcinoma of the colon or rectum with locally advanced or metastatic disease
- Evidence of measurable disease per Response Evaluation Criteria in Solid Tumors
(RECIST)
- Eastern Cooperative Oncology Group (ECOG) 0 or 1
Exclusion criteria
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- Previous treatment with Sutent, Avastin, or any other systemic therapy for locally
advanced or metastatic colorectal cancer
- Less than 6 months since completion of adjuvant chemotherapy to documentation of
recurrent disease
- History of cardiac disease
- Brain mets