A Study of the Efficacy and Safety of Aricept in Patients With Severe Alzheimer's Disease Who Are Living in Skilled Nursing Homes

Back to Search
Print
Bookmark Trial

NCT00630851

Last updated date
Back to Search
Print
Bookmark Trial
FOR MORE INFORMATION
Study Location
Pfizer Investigational Site
Akersberga, , 184 33 AKERSBERGA, Sweden
See other locations
Contact
1-800-718-1021
[email protected]
Related Links

FOR MORE INFORMATION

Contact a representative by phone, email, or visiting the study website. Please see the references below:

By phone

Pfizer Clinical Trials Contact Center

1-800-718-1021

By email

Contact

[email protected]

Call Now

Eligibility Criteria
condition
The disease, disorder, syndrome, illness, or injury that is being studied.
Alzheimer Disease
Sex
Females and Males
Age
Pediatric Trials: 0-17 Years
Adult Trials: 18+ Years
50 + years
Inclusion Criteria
The factors, or reasons, that allow a person to participate in a clinical study.
Show details

- Probable or possible Alzheimer's disease

- Living in skilled nursing home

Exclusion Criteria
The factors, or reasons, that prevent a person from participating in a clinical study.
Show details


- Other types of dementia or psychiatric or neurologic disorders


- Musculoskeletal disease

NEED INFO?

Questions about a trial? Call or email to reach a Pfizer Clinical Trial Contact Center Representative

Pfizer Clinical Trials Contact Center

1-800-718-1021

[email protected]

Call Now
pfizer-logoClinical Trials
Interested in learning more about clinical trials?
Discover how clinical trials work and the impact your participation could have.
Learn more ›

TRY A NEW SEARCH

Search for Clinical Trials by condition, keyword or trial number. Share your location or enter your city or zip code to find studies near you.

Advanced Search

Based on your search, you may also be interested in

Alzheimer DiseaseLipitor as a Treatment for Alzheimer's Disease
NCT00024531
  1. Sun City, Arizona
ALL GENDERS
50 Years+
years
MULTIPLE SITES
Alzheimer DiseaseStudy Evaluating The Efficacy And Safety Of Bapineuzumab In Alzheimer Disease Patients
NCT00667810
  1. Birmingham, Alabama
  2. Goodyear, Arizona
  3. Phoenix, Arizona
  4. Phoenix, Arizona
  5. Phoenix, Arizona
  6. Phoenix, Arizona
  7. Little Rock, Arkansas
  8. Costa Mesa, California
  9. Encino, California
  10. Fresno, California
  11. Laguna Hills, California
  12. Laguna Hills, California
  13. Loma Linda, California
  14. Loma Linda, California
  15. Long Beach, California
  16. Los Alamitos, California
  17. Newport Beach, California
  18. San Diego, California
  19. San Diego, California
  20. San Diego, California
  21. San Diego, California
  22. San Diego, California
  23. San Diego, California
  24. San Francisco, California
  25. Boulder, Colorado
  26. Boulder, Colorado
  27. Denver, Colorado
  28. Danbury, Connecticut
  29. Fairfield, Connecticut
  30. Greenwich, Connecticut
  31. Greenwich, Connecticut
  32. New Haven, Connecticut
  33. New Haven, Connecticut
  34. New Haven, Connecticut
  35. New Haven, Connecticut
  36. New Haven, Connecticut
  37. New Haven, Connecticut
  38. New Haven, Connecticut
  39. New Haven, Connecticut
  40. Norwalk, Connecticut
  41. Waterbury, Connecticut
  42. Atlantis, Florida
  43. Atlantis, Florida
  44. Bradenton, Florida
  45. Deerfield Beach, Florida
  46. Delray Beach, Florida
  47. Fort Lauderdale, Florida
  48. Hallandale Beach, Florida
  49. Ocala, Florida
  50. Ocala, Florida
  51. Orlando, Florida
  52. Palm Beach Gardens, Florida
  53. Port Charlotte, Florida
  54. Sarasota, Florida
  55. Sun City, Florida
  56. Tampa, Florida
  57. West Palm Beach, Florida
  58. Atlanta, Georgia
  59. Columbus, Georgia
  60. Columbus, Georgia
  61. Decatur, Georgia
  62. Decatur, Georgia
  63. Lawerenceville, Georgia
  64. Lawrenceville, Georgia
  65. Elk Grove Village, Illinois
  66. Elk Grove Village, Illinois
  67. Peoria, Illinois
  68. Peoria, Illinois
  69. Peoria, Illinois
  70. Peoria, Illinois
  71. Springfield, Illinois
  72. Springfield, Illinois
  73. Elkhart, Indiana
  74. Mishawaka, Indiana
  75. Wichita, Kansas
  76. Wichitia, Kansas
  77. Paducah, Kentucky
  78. Paducah, Kentucky
  79. Lake Charles, Louisiana
  80. New Orleans, Louisiana
  81. Shreveport, Louisiana
  82. Bethesda, Maryland
  83. Rockville, Maryland
  84. Boston, Massachusetts
  85. Boston, Massachusetts
  86. Boston, Massachusetts
  87. Boston, Massachusetts
  88. Boston, Massachusetts
  89. Boston, Massachusetts
  90. Boston, Massachusetts
  91. Haverhill, Massachusetts
  92. Newton, Massachusetts
  93. Springfield, Massachusetts
  94. Ann Arbor, Michigan
  95. Ann Arbor, Michigan
  96. Ann Arbor, Michigan
  97. East Lansing, Michigan
  98. Lansing, Michigan
  99. Flowood, Mississippi
  100. Flowood, Mississippi
  101. Hattiesburg, Mississippi
  102. Kansas City, Missouri
  103. Great Falls, Montana
  104. Great Falls, Montana
  105. Berlin, New Jersey
  106. Eatontown, New Jersey
  107. Manchester, New Jersey
  108. Toms River, New Jersey
  109. Brewster, New York
  110. Liverpool, New York
  111. Rochester, New York
  112. Rochester, New York
  113. Asheville, North Carolina
  114. Charlotte, North Carolina
  115. Hickory, North Carolina
  116. Hickory, North Carolina
  117. Raleigh, North Carolina
  118. Raleigh, North Carolina
  119. Raleigh, North Carolina
  120. Raleigh, North Carolina
  121. Columbus, Ohio
  122. Columbus, Ohio
  123. Columbus, Ohio
  124. Columbus, Ohio
  125. Toledo, Ohio
  126. Oklahoma City, Oklahoma
  127. Oklahoma City, Oklahoma
  128. Oklahoma City, Oklahoma
  129. Portland, Oregon
  130. Abington, Pennsylvania
  131. Abington, Pennsylvania
  132. Jenkintown, Pennsylvania
  133. Philadelphia, Pennsylvania
  134. Philadelphia, Pennsylvania
  135. Philadelphia, Pennsylvania
  136. Philadelphia, Pennsylvania
  137. Philadelphia, Pennsylvania
  138. Philadelphia, Pennsylvania
  139. Pittsburgh, Pennsylvania
  140. Willow Grove, Pennsylvania
  141. East Providence, Rhode Island
  142. Pawtucket, Rhode Island
  143. Providence, Rhode Island
  144. Charleston, South Carolina
  145. Charleston, South Carolina
  146. Greer, South Carolina
  147. North Charleston, South Carolina
  148. Cordova, Tennessee
  149. Austin, Texas
  150. Austin, Texas
  151. Dallas, Texas
  152. Fort Worth, Texas
  153. San Antonio, Texas
  154. San Antonio, Texas
  155. San Antonio, Texas
  156. San Antonio, Texas
  157. Wichita Falls, Texas
  158. Bennington, Vermont
  159. Bennington, Vermont
  160. Charlottesville, Virginia
  161. Charlottesville, Virginia
  162. Charlottesville, Virginia
  163. Bothell, Washington
  164. Seattle, Washington
  165. Buenos Aires,
  166. Buenos Aires,
  167. Gosford, New South Wales
  168. Hornsby, New South Wales
  169. Woodville South, South Australia
  170. Ballarat, Victoria
  171. West Heidelberg, Victoria
  172. Nedlands, Western Australia
  173. Nedlands, Western Australia
  174. Adelaide SA,
  175. Antwerpen,
  176. Brugge,
  177. Bruxelles,
  178. Edegem,
  179. Leuven,
  180. Roeselare,
  181. North York, Ontario
  182. Ottawa, Ontario
  183. Toronto, Ontario
  184. Toronto, Ontario
  185. L'Ancienne-Lorette, Quebec
  186. Montreal, Quebec
  187. Montreal, Quebec
  188. Sherbrooke, Quebec
  189. Quebec,
  190. Santiago,
  191. Santiago,
  192. Zagreb,
  193. Zagreb,
  194. Kuopio,
  195. Turku,
  196. Rennes, Cedex
  197. Amiens,
  198. Bron,
  199. Caen,
  200. Colmar,
  201. Dijon,
  202. Lille,
  203. Marseille,
  204. Marseille,
  205. Montpellier,
  206. Nantes - Saint Herblain,
  207. Nice,
  208. Paris Cedex 13,
  209. Paris,
  210. Poitiers,
  211. Reims,
  212. Rouen,
  213. Toulouse,
  214. Toulouse,
  215. Berlin,
  216. Bochum,
  217. Offenburg,
  218. Regensburg,
  219. Ancona,
  220. Brescia,
  221. Catania,
  222. Chieti,
  223. Firenze,
  224. Milano,
  225. Milano,
  226. Milano,
  227. Monza,
  228. Monza,
  229. Roma,
  230. Roma,
  231. Siena,
  232. Nagoya, Aichi,
  233. Ota-ku, Tokyo
  234. Aichi,
  235. Chiba,
  236. Chiba,
  237. Chiba,
  238. Fukuoka,
  239. Gunma,
  240. Gunma,
  241. Gunma,
  242. Hiroshima,
  243. Hyogo,
  244. Hyogo,
  245. Hyogo,
  246. Iwate,
  247. Kagawa,
  248. Kanagawa,
  249. Kanagawa,
  250. Kanagawa,
  251. Kyoto,
  252. Kyoto,
  253. Kyoto,
  254. Nagano,
  255. Niigata,
  256. Okayama,
  257. Okayama,
  258. Osaka,
  259. Osaka,
  260. Osaka,
  261. Shizuoka,
  262. Tokyo,
  263. Tokyo,
  264. Tokyo,
  265. Tokyo,
  266. Tokyo,
  267. Seongnam-si, Gyeonggi-do
  268. Seoul,
  269. Monterrey, Nuevo León
  270. Aguascalientes,
  271. 's-Hertogenbosch,
  272. Amsterdam,
  273. Breda,
  274. Eindhoven,
  275. Haarlem,
  276. Leeuwarden,
  277. s. Hertogenbosch,
  278. Auckland, NZ
  279. Christchurch,
  280. Bydgoszcz,
  281. Kielce,
  282. Krakow,
  283. Poznan,
  284. Warszawa,
  285. Warszawa,
  286. Amadora,
  287. Coimbra,
  288. Lisboa,
  289. Kazan,
  290. Nizhny Novgorod,
  291. Saint-Petersburg,
  292. Saint-Petersburg,
  293. Saint-Petersburg,
  294. Saint-Petersburg,
  295. Novi Sad, Vojvodina
  296. Belgrade,
  297. Beograd,
  298. Kragujevac,
  299. Bratislava,
  300. Bratislava,
  301. Bratislava,
  302. Bratislava,
  303. Martin,
  304. Michalovce,
  305. Rimavska Sobota,
  306. Zilina,
  307. Johannesburg, Gauteng
  308. Johannesburg, Gauteng
  309. Pretoria, Gauteng
  310. Durban, Kwa Zulu Natal
  311. Panorama, Western Cape
  312. Elche, Alicante
  313. Terrassa, Barcelona
  314. Plasencia, Caceres
  315. Palma de Mallorca, Islas Baleares
  316. Palma de Mallorca, Islas Baleares
  317. Baracaldo,
  318. Barcelona,
  319. Barcelona,
  320. Barcelona,
  321. Barcelona,
  322. Burgos,
  323. Madrid,
  324. Madrid,
  325. Madrid,
  326. Madrid,
  327. Madrid,
  328. Murcia,
  329. Malmo,
  330. Uppsala,
  331. Uppsala,
  332. Uppsala,
  333. Basel, BS
  334. Les Acacias, GE
  335. Lausanne, VD
  336. Thonex-Geneva,
  337. Blackpool, Lancashire
  338. Bradford, West Yorkshire
  339. Brighton,
  340. Glasgow,
  341. London,
  342. London,
  343. Newcastle upon Tyne,
  344. Northampton,
  345. Penarth,
  346. Sheffield,
  347. Sheffield,
  348. Swindon,
ALL GENDERS
50 Years+
years
MULTIPLE SITES
Alzheimer DiseaseStudy Evaluating PAZ-417 in Cerebrospinal Fluid in Subjects With Alzheimer's Disease
NCT00739037
  1. Glendale, California
ALL GENDERS
55 Years+
years
MULTIPLE SITES
Alzheimer DiseaseStudy Evaluating the Safety and Efficacy of Bapineuzumab in Alzheimer Disease Patients
NCT00676143
  1. Birmingham, Alabama
  2. Birmingham, Alabama
  3. Birmingham, Alabama
  4. Birmingham, Alabama
  5. Goodyear, Arizona
  6. Phoenix, Arizona
  7. Phoenix, Arizona
  8. Phoenix, Arizona
  9. Phoenix, Arizona
  10. Little Rock, Arkansas
  11. Carson, California
  12. Long Beach, California
  13. San Francisco, California
  14. Boulder, Colorado
  15. Boulder, Colorado
  16. Denver, Colorado
  17. Fairfield, Connecticut
  18. Greenwich, Connecticut
  19. Greenwich, Connecticut
  20. New Haven, Connecticut
  21. New Haven, Connecticut
  22. New Haven, Connecticut
  23. New Haven, Connecticut
  24. New Haven, Connecticut
  25. New Haven, Connecticut
  26. New Haven, Connecticut
  27. Norwalk, Connecticut
  28. Atlantis, Florida
  29. Atlantis, Florida
  30. Atlantis, Florida
  31. Delray Beach, Florida
  32. Orlando, Florida
  33. Palm Beach Gardens, Florida
  34. Port Charlotte, Florida
  35. Sarasota, Florida
  36. Tampa, Florida
  37. Decatur, Georgia
  38. Decatur, Georgia
  39. Lawrenceville, Georgia
  40. Elk Grove Village, Illinois
  41. Springfield, Illinois
  42. Springfield, Illinois
  43. Kansas City, Kansas
  44. Lake Charles, Louisiana
  45. Boston, Massachusetts
  46. Boston, Massachusetts
  47. Boston, Massachusetts
  48. Boston, Massachusetts
  49. Boston, Massachusetts
  50. Boston, Massachusetts
  51. Boston, Massachusetts
  52. Dartmouth, Massachusetts
  53. Pittsfield, Massachusetts
  54. Springfield, Massachusetts
  55. Ann Arbor,, Michigan
  56. Ann Arbor, Michigan
  57. Ann Arbor, Michigan
  58. Ann Arbor, Michigan
  59. East Lansing, Michigan
  60. Hattiesburg, Mississippi
  61. Kansas City, Missouri
  62. Eatontown, New Jersey
  63. Edison, New Jersey
  64. Manchester, New Jersey
  65. Liverpool, New York
  66. Raleigh, North Carolina
  67. Raleigh, North Carolina
  68. Raleigh, North Carolina
  69. Raleigh, North Carolina
  70. Columbs, Ohio
  71. Columbs, Ohio
  72. Columbus, Ohio
  73. Portland, Oregon
  74. Portland, Oregon
  75. Portland, Oregon
  76. Portland, Oregon
  77. Silverton, Oregon
  78. Abington, Pennsylvania
  79. Abington, Pennsylvania
  80. Abington, Pennsylvania
  81. Flourtown, Pennsylvania
  82. Jenkintown, Pennsylvania
  83. Philadelphia, Pennsylvania
  84. Philadelphia, Pennsylvania
  85. Philadelphia, Pennsylvania
  86. Philadelphia, Pennsylvania
  87. Philadelphia, Pennsylvania
  88. Philadelphia, Pennsylvania
  89. Willow Grove, Pennsylvania
  90. East Providence, Rhode Island
  91. Pawtucket, Rhode Island
  92. Providence, Rhode Island
  93. Charleston, South Carolina
  94. Charleston, South Carolina
  95. Charleston, South Carolina
  96. North Charleston, South Carolina
  97. Dallas, Texas
  98. San Antonio, Texas
  99. San Antonio, Texas
  100. San Antonio, Texas
  101. San Antonio, Texas
  102. San Antonio, Texas
  103. San Antonio, Texas
  104. San Antonio, Texas
  105. Bennington, Vermont
  106. Bennington, Vermont
  107. Madison, Wisconsin
  108. Madison, Wisconsin
  109. Madison, Wisconsin
  110. Madison, Wisconsin
  111. Madison, Wisconsin
  112. Buenos Aires,
  113. Buenos Aires,
  114. Buenos Aires,
  115. Cordoba,
  116. Gosford, New South Wales
  117. Gosford, New South Wales
  118. Hornsby, New South Wales
  119. Adelaide, South Australia
  120. Woodville South, South Australia
  121. Ballarat, Victoria
  122. West Heidelberg, Victoria
  123. Nedlands, Western Australia
  124. Nedlands, Western Australia
  125. Graz,
  126. Klagenfurt,
  127. Wien,
  128. Wien,
  129. Wien,
  130. Antwerpen,
  131. Brugge,
  132. Brussels,
  133. Edegem,
  134. Leuven,
  135. Roeselare,
  136. Santiago,
  137. Santiago,
  138. Zagreb,
  139. Kuopio,
  140. Turku,
  141. Bordeaux Cedex,
  142. Bron,
  143. Caen,
  144. Caen,
  145. Colmar,
  146. Dijon,
  147. Lille,
  148. Marseille,
  149. Montpellier,
  150. Nantes - Saint Herblain,
  151. Nice,
  152. Nice,
  153. Paris,
  154. Paris,
  155. Poitiers,
  156. Reims,
  157. Rennes Cedex,
  158. Rouen,
  159. Toulouse,
  160. Toulouse,
  161. Berlin,
  162. Bochum,
  163. Dresden,
  164. Freiburg,
  165. Offenburg,
  166. Ulm,
  167. Ancona,
  168. Ancona,
  169. Brescia,
  170. Catania,
  171. Catania,
  172. Chieti,
  173. Milano,
  174. Monza,
  175. Roma,
  176. Roma,
  177. Siena,
  178. Nagoya, Aichi,
  179. Kiyose, Tokyo
  180. Aichi,
  181. Chiba,
  182. Chiba,
  183. Chiba,
  184. Fukuoka,
  185. Gunma,
  186. Gunma,
  187. Gunma,
  188. Hiroshima,
  189. Hyogo,
  190. Hyogo,
  191. Hyogo,
  192. Iwate,
  193. Kagawa,
  194. Kanagawa,
  195. Kanagawa,
  196. Kanagawa,
  197. Kyoto,
  198. Kyoto,
  199. Kyoto,
  200. Nagano,
  201. Niigata,
  202. Okayama,
  203. Okayama,
  204. Osaka,
  205. Osaka,
  206. Osaka,
  207. Shizuoka,
  208. Tokyo,
  209. Tokyo,
  210. Tokyo,
  211. Tokyo,
  212. Tokyo,
  213. Monterrey, Nuevo León
  214. Aguascalientes,
  215. Breda, Noord Brabant
  216. Hilversum, Noord Holland
  217. Haarlem, The Netherlands
  218. 's-Hertogenbosch,
  219. Alkmaar,
  220. Amsterdam,
  221. Eindhoven,
  222. Leeuwarden,
  223. Rotterdam,
  224. Auckland, NZ
  225. Christchurch,
  226. Bydgoszcz,
  227. Krakow,
  228. Poznan,
  229. Warszawa,
  230. Warszawa,
  231. Amadora,
  232. Coimbra,
  233. Lisboa,
  234. Belgrade,
  235. Kragujevac,
  236. Novi Sad,
  237. Sremska Kamenica,
  238. Sremska Kamenica,
  239. Bratislava,
  240. Bratislava,
  241. Michalovce,
  242. Rimavska Sobota,
  243. Johannesburg, Gauteng
  244. Johannesburg, Gauteng
  245. Pretoria, Gauteng
  246. Durban, Kwa Zulu Natal
  247. Bellville, Western Cape
  248. Panorama, Western Cape
  249. Elche, Alicante
  250. Terrassa, Barcelona
  251. Plasencia, Caceres
  252. Palma de Mallorca, Islas Baleares
  253. Palma de Mallorca, Islas Baleares
  254. San Sebastian, Pais Vasco
  255. Baracaldo, Vizcalla
  256. Barcelona,
  257. Barcelona,
  258. Barcelona,
  259. Barcelona,
  260. Burgos,
  261. Madrid,
  262. Madrid,
  263. Madrid,
  264. Madrid,
  265. Madrid,
  266. Murcia,
  267. Malmo,
  268. Uppsala,
  269. Uppsala,
  270. Uppsala,
  271. Basel, BS
  272. Les Acacias, GE
  273. Lausanne, VD
  274. Thonex-Geneva,
  275. Blackpool, Lancashire
  276. Trafford Park, Manchester
  277. Bradford,
  278. Brighton,
  279. Glasgow,
  280. London,
  281. London,
  282. Newcastle upon Tyne,
  283. Northampton,
  284. Penarth,
  285. Sheffield,
  286. Sheffield,
  287. Swindon,
ALL GENDERS
50 Years+
years
MULTIPLE SITES
Advanced Information
Descriptive Information
Brief Title  ICMJE A Study of the Efficacy and Safety of Aricept in Patients With Severe Alzheimer's Disease Who Are Living in Skilled Nursing Homes
Official Title  ICMJE A Six-month, Multicenter, Double-blind, Parallel, Placebo-controlled Study of the Effect on Global/Behavioural/ADL Functions and Tolerability of Aricept in Patients Wtih Severe Alzheimer's Disease Living in an Assisted Care Facility
Brief Summary The purpose of the study is to evaluate the efficacy and safety of Aricept in nursing home patients with severe Alzheimer's disease.
Detailed Description Not Provided
Study Type  ICMJE Interventional
Study Phase  ICMJE Phase 3
Study Design  ICMJE Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double
Primary Purpose: Treatment
Condition  ICMJE Alzheimer Disease
Intervention  ICMJE
  • Drug: Donepezil (Aricept)
    Donepezil (Aricept) 5 mg tablet orally once daily for 30 days, followed by 10 mg tablet orally once daily to complete 6 months of treatment
  • Drug: Placebo
    Matching placebo tablets orally once daily for 6 months
Study Arms  ICMJE
  • Experimental: 1
    Intervention: Drug: Donepezil (Aricept)
  • Placebo Comparator: 2
    Intervention: Drug: Placebo
Publications * Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruitment Information
Recruitment Status  ICMJE Completed
Actual Enrollment  ICMJE
 (submitted: April 22, 2011)		249
Original Estimated Enrollment  ICMJE
 (submitted: February 27, 2008)		280
Actual Study Completion Date  ICMJE October 2004
Primary Completion Date Not Provided
Eligibility Criteria  ICMJE

Inclusion Criteria:

  • Probable or possible Alzheimer's disease
  • Living in skilled nursing home

Exclusion Criteria:

  • Other types of dementia or psychiatric or neurologic disorders
  • Musculoskeletal disease
Sex/Gender  ICMJE
Sexes Eligible for Study:All
Ages  ICMJE 50 Years and older   (Adult, Older Adult)
Accepts Healthy Volunteers  ICMJE No
Contacts  ICMJE Contact information is only displayed when the study is recruiting subjects
Listed Location Countries  ICMJE Sweden
Removed Location Countries  
 
Administrative Information
NCT Number  ICMJE NCT00630851
Other Study ID Numbers  ICMJE A2501017
Has Data Monitoring Committee Yes
U.S. FDA-regulated Product Not Provided
IPD Sharing Statement  ICMJE Not Provided
Responsible Party Director, Clinical Trial Disclosure Group, Pfizer, Inc.
Study Sponsor  ICMJE Pfizer
Collaborators  ICMJE Not Provided
Investigators  ICMJE
Study Director:Pfizer CT.gov Call CenterPfizer
PRS Account Pfizer
Verification Date March 2015

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP