- Man or nonlactating and nonpregnant woman, aged 18 to 70 years, inclusive, at the
- Must meet criteria for rheumatoid arthritis with functional class I to III.
- Diagnosis of rheumatoid arthritis more than 6 months before study day 1 and
rheumatoid arthritis onset after 16 years of age
- Any significant health problems other than rheumatoid arthritis.
- Treatment of greater than 10 mg of prednisone per day.
- Treatment with cyclophosphamide.