Outpatients with an acute pharyngitis erythematous or erythematopultaceous with
modification of pharynx aspect and fever of ≥38° C, and patients either with or without
spontaneous pharyngeal pain or upon swallowing and enlargement of the cervical lymph node
(mandibular area) were eligible for inclusion. All subjects should have had a positive
rapid strep test and a positive culture for Group A beta-hemolytic streptococcus.
Patients with pseudomembranous, vesicular, ulcerous or ulceronecrotic pharyngitis were