- Osteoarthritis of the knee as defined by the American College of Rheumatology criteria
in a flare state at baseline visit
- Functional Capacity Classification of I-III
- Inflammatory arthritis or gout/pseudo-gout with an acute flare within the past 2 years
(subjects with fibrositis or fibromyalgia will not be excluded)
- Received acetaminophen within 24 hours of the baseline visit
- Acute joint trauma at index joint within the past 3 months with active symptoms
- History of gastrointestinal (GI) perforation, obstruction, or bleeding
- Diagnosed or treated for GI ulcer within 60 days prior to first dose of study
medication
- Received corticosteroids or hyaluronic acid within certain timeframe before study